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Gene Page - CG Number : CG11375
Gene Summary - CG11375:

CG11375: The gene polybromo is referred to in FlyBase by the symbol Dmel\polybromo (CG11375, FBgn0039227). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding; zinc ion binding. There is experimental evidence that it is involved in the biological process: eggshell chorion assembly; negative regulation of chromatin silencing; vitelline membrane formation involved in chorion-containing eggshell formation; imaginal disc-derived leg morphogenesis. 9 alleles are reported. The phenotypes of these alleles are annotated with: chorion; vitelline membrane; adult abdominal segment 6. It has one annotated transcript and one annotated polypeptide. Protein features are: Bromo adjacent homology (BAH) domain; Bromodomain; Bromodomain, conserved site; High mobility group, superfamily; Zinc finger, C2H2-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG11375 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11375:CG11375 is not perturbed in primary screen.
CG11375 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11375.
Cell Count:
CG11375Primary screen295196337
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11375:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11375 is not tested in classification assay
Integrated Annotations for CG11375 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
eggshell chorion assemblyGO:0007306inferred from mutant phenotype
vitelline membrane formation involved in chorion-containing eggshell formation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
polytene chromosomeGO:0005700inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
DNA bindingGO:0003677inferred from electronic annotation with InterPro:IPR000910, InterPro:IPR001025
zinc ion binding
Other annotations
FlyBaseClick here to see CG11375 in FlyBase
FLIGHTClick here to see CG11375 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11375 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11375
Entrez GeneEntrez Gene page for CG11375
UniprotUniprot page for CG11375

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)