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Gene Page - CG Number : CG11376
Gene Summary - CG11376:

CG11376: The gene Zizimin-related is referred to in FlyBase by the symbol Dmel\Zir (CG11376, FBgn0031216). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: guanyl-nucleotide exchange factor activity. There is experimental evidence that it is involved in the biological process: phagocytosis; encapsulation of foreign target; melanotic encapsulation of foreign target. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Dedicator of cytokinesis; Dedicator of cytokinesis C; Dedicator of cytokinesis C-terminal; Dedicator of cytokinesis C/D, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.

Gene summary for CG11376 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11376:CG11376 is not perturbed in primary screen.
CG11376 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11376.
Cell Count:
CG_NumberCategoryR1R2R3
CG11376Primary screen393148271
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11376:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211693.6360631066.0405957617.7621793870.708221020.4775445681.4846822126.4391069611.443797151.591564073-0.1581880110.3965393540.128787277-0.136035996-0.0288899930.6290632550.0313916221.3363374880.76114980.4963130993.2160869230.222415661-0.17378809-0.045401674
212217-1.089453807-1.636567674-0.8452332480.741648713-1.661378403-0.2631368580.608033792-0.414245363-0.6214742092.0456574381.525390141-0.2469254023.0086451862.9864305131.718040367-1.5572647514.645307445-0.2263876481.0743205980.230482748-0.3520349151.3057794570.228102412
213671.0270533451.1786632380.9899943030.2119674480.1060369270.6190350650.2467199280.8465080910.8083658150.988489456-0.39379535-0.2388840080.0497729910.4736212950.121354715-0.3806777390.207264682-0.5611472050.824306731.3205881512.714653542-0.964010159-0.725039715
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11376 is not tested in classification assay
Integrated Annotations for CG11376 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
melanotic encapsulation of foreign targetGO:0035011inferred from mutant phenotype
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
GTP bindingGO:0005525inferred from electronic annotation with InterPro:IPR010703
guanyl-nucleotide exchange factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11376 in FlyBase
FLIGHTClick here to see CG11376 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11376 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11376
Entrez GeneEntrez Gene page for CG11376
UniprotUniprot page for CG11376

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)