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Gene Page - CG Number : CG11377
Gene Summary - CG11377:

CG11377: This gene is referred to in FlyBase by the symbol Dmel\CG11377 (FBgn0031217). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: calcium ion binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Domain of unknown function DUF3456; EGF-like calcium-binding; EGF-like calcium-binding, conserved site; EGF-like, conserved site; EGF-like, laminin; Epidermal growth factor-like domain; Furin-like repeat; Growth factor, receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.

Gene summary for CG11377 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11377:CG11377 is perturbed in following parameters in primary screen: Fmph2
CG11377 is perturbed in following parameters in classification assay (fluid): LP_Fint1+ LP_Fint4- NuCirc-(fld) NuFluct+(fld) NuSize+(fld) Okt-(fld) Rto1+ SP_Fint1+ SP_Fint2+
CG11377 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11377.
Cell Count:
CG_NumberCategoryR1R2R3
CG11377Primary screen289603460
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11377:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
21170-0.0038638711.2932976973.462156319-1.1844246710.2055832832.346199494.3198202760.839758280.9480568920.242249211.109552835-0.2542956210.170742670.0365968271.308833159-0.6099473860.8565388931.5226136320.1037445122.176021156-0.0110117230.512073360.14884985
2122160.4155060110.8725190741.9601213231.399285340.8576324534.0589335165.3775334573.6132163723.1153755390.5113102012.0421884-0.0662925450.7674507020.594794296-0.98285682-0.0243127791.8550426291.0706303411.6609493234.2702155881.170953332.4903665090.665750544
21366-0.690207126-0.421901034-0.4838603420.8487409881.1511553651.3626176580.4795383611.5555682852.589112093-0.1071895260.1230048430.176422433-0.2556348-0.186567677-0.0035630490.510076812-0.1571466970.0580940530.6844421.7381782830.42371259-0.412105378-0.000932747
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11377Slide20C0.1331.1451.2001.224
CG11377Slide20O0.0320.8120.6010.637
CG11377Slide20P0.1371.0181.1841.137
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11377 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
-
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
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Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
calcium ion bindingGO:0005509inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097
Other annotations
DatabaseLink
FlyBaseClick here to see CG11377 in FlyBase
FLIGHTClick here to see CG11377 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11377 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11377
Entrez GeneEntrez Gene page for CG11377
UniprotUniprot page for CG11377

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)