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Gene Page - CG Number : CG11423
Gene Summary - CG11423:

CG11423: This gene is referred to in FlyBase by the symbol Dmel\CG11423 (FBgn0034251). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: NADH dehydrogenase (ubiquinone) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: NADH ubiquinone oxidoreductase, F subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; NADH:ubiquinone oxidoreductase, 51kDa subunit; NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site; Soluble ligand binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed in adult male stages.

Gene summary for CG11423 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11423:CG11423 is not perturbed in primary screen.
CG11423 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11423.
Cell Count:
CG_NumberCategoryR1R2R3
CG11423Primary screen7396361
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11423:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211915.6202579041.0250572870.6798848981.840767118-1.523958706-2.842673855-1.417555429-2.210605579-5.002054501-0.996635317-0.847655206-1.037000701-1.4065749740.045163721-1.100128104-0.963079319-0.362821462-2.0236707780.501131553-4.9143080280.815018390.849184261.108440529
2122550.301068238-0.6212029470.074063254-0.66541614-1.901296803-1.745904949-1.240416169-1.243223166-3.849556992-1.438600726-1.340747148-0.540315242-1.1055859-0.5380872590.011249206-1.937135882-1.516862549-1.307296174-0.70357311-3.3704820870.679017116-0.234596127-1.498334281
21345-0.683565897-0.3558409070.322754402-0.3754298960.2943498010.9789958920.102079591.3584641222.304386601-0.207812858-0.1290093270.230630531-0.3937339930.2117217990.976601969-0.1299581361.1403488861.3337489580.7882548531.2121308650.00674327-0.24334837-0.393925889
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11423 is not tested in classification assay
Integrated Annotations for CG11423 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
oxidation-reduction processGO:0055114inferred from electronic annotation with InterPro:IPR001949, InterPro:IPR011537, InterPro:IPR019575
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
mitochondrial respiratory chain complex IGO:0005747inferred from sequence or structural similarity with EMBL:AF053070
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
NADH dehydrogenase (ubiquinone) activityGO:0008137inferred from sequence or structural similarity with EMBL:AF053070
NAD binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11423 in FlyBase
FLIGHTClick here to see CG11423 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11423 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11423
Entrez GeneEntrez Gene page for CG11423
UniprotUniprot page for CG11423

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)