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Gene Page - CG Number : CG11426
Gene Summary - CG11426:

CG11426: This gene is referred to in FlyBase by the symbol Dmel\CG11426 (FBgn0037166). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphatidate phosphatase activity. There is experimental evidence that it is involved in the biological process: phototransduction. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Phosphatidic acid phosphatase type 2/haloperoxidase; Phosphatidic acid phosphatase/chloroperoxidase, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed in adult male stages.

Gene summary for CG11426 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11426:CG11426 is perturbed in following parameters in primary screen: Fmph2
CG11426 is perturbed in following parameters in classification assay (fluid): LP_Fint1+ LP_Fint4- NuCellD-(fld) NuSize+(fld) Rto2- Rto3-
CG11426 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11426.
Cell Count:
CG_NumberCategoryR1R2R3
CG11426Primary screen359594163
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11426:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211930.3573867020.4716256811.174003263-0.0668976470.2133036571.3127122413.3602832612.3270579081.374808012-0.0291256192.201570128-0.4058405440.7543027610.643867238-0.7743038540.0337196311.1119206883.0228013290.9451499691.3509379490.907875449-0.0764292562.84328966
2122531.4390437393.6342827355.10011895-0.009683231.4997375967.8984652428.8318631698.9270456943.9920273460.2199489891.2950084080.6159745111.6548928211.02576978-0.248154890.3460249972.7436068451.5794880942.6227967925.82514019-0.4145773424.4062330162.21333131
21343-0.8513518020.231499349-0.2359558931.092395545-0.06176988-0.774143867-0.852594804-0.836556373-2.2011818250.103868684-1.443461623-0.81594472-0.8260095590.3673675330.086184622-0.2316965920.109003091-0.08662625-1.027663151-1.9879205142.264729613-0.7765830110.375105009
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11426Slide20C0.2740.9681.2441.539
CG11426Slide20O0.7951.0430.8951.133
CG11426Slide20P0.3880.9181.2671.157
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11426 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
dephosphorylationGO:0016311non-traceable author statement
phototransduction
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
membraneGO:0016020inferred from electronic annotation with InterPro:IPR000326
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
phosphatidate phosphatase activityGO:0008195non-traceable author statement
phosphatidate phosphatase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11426 in FlyBase
FLIGHTClick here to see CG11426 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11426 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11426
Entrez GeneEntrez Gene page for CG11426
UniprotUniprot page for CG11426

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)