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Gene Page - CG Number : CG11430
Gene Summary - CG11430:

CG11430: The gene olf186-F is referred to in FlyBase by the symbol Dmel\olf186-F (CG11430, FBgn0041585). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: store-operated calcium channel activity. There is experimental evidence that it is involved in the biological process: nervous system development; positive regulation of calcium ion transport; positive regulation of NFAT protein import into nucleus; store-operated calcium entry. 28 alleles are reported. The phenotype of these alleles is annotated with: dorsal medial muscle. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Calcium release-activated calcium channel protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG11430 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11430:CG11430 is not perturbed in primary screen.
CG11430 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11430.
Cell Count:
CG_NumberCategoryR1R2R3
CG11430Primary screen96148195
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11430:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211961.5814718944.6539241093.140737449-0.023109405-0.7933248342.8316165757.7208225363.900780475-1.428740717-1.1406912410.2041149470.4584940371.683526620.946360949-0.353806179-1.2256183581.615069268-0.1652979314.9198749440.959075026-0.376244453-0.6707953011.593950489
2122500.684140221-0.1056277470.533131409-0.358633844-1.337607364-0.4900914921.52868187-0.330443357-1.264826531-0.082260623-0.003042381-0.133225142-0.987660339-0.593183763-0.501280933-1.0117741850.247888573-1.180144953-0.148577384-0.4065274032.032996685-0.317997927-0.638945359
21340-0.681300046-0.426288565-0.93986269-0.390756007-0.971439072-0.052978932-0.5734553410.107796243-1.354068547-0.039775816-1.193918143-0.46814354-1.105166687-0.297457325-0.748300473-0.1046531-0.142331016-1.7424900910.779103331-1.1256108432.641430176-0.842465249-0.330445497
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11430 is not tested in classification assay
Integrated Annotations for CG11430 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
positive regulation of NFAT protein import into nucleusGO:0051533inferred from mutant phenotype
positive regulation of calcium ion transport
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021non-traceable author statement
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
serine-type endopeptidase activityGO:0004252NOT non-traceable author statement
store-operated calcium channel activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11430 in FlyBase
FLIGHTClick here to see CG11430 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11430 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11430
Entrez GeneEntrez Gene page for CG11430
UniprotUniprot page for CG11430

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)