Gene Page - CG Number : CG11440

Gene Summary - CG11440:

CG11440: The gene lazaro is referred to in FlyBase by the symbol Dmel\laza (CG11440, FBgn0037163). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphatidate phosphatase activity. There is experimental evidence that it is involved in the biological process: response to light intensity; phototransduction; thermotaxis. 12 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; eye. It has one annotated transcript and one annotated polypeptide. Protein features are: Phosphatidic acid phosphatase type 2/haloperoxidase; Phosphatidic acid phosphatase/chloroperoxidase, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages.

Gene summary for CG11440 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)

Experimental Summary - CG11440:

CG11440 is not perturbed in primary screen.
CG11440 is not tested in classification assay.

Cellular phenotyping(Images):

Click here to access phenotyping images of gene CG11440.

Cell Count:

CG_Number	Category	R1	R2	R3
CG11440	Primary screen	526	214	130

R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3

Primary screen data - CG11440:

SN	RN	WN	Fint1	Fint2	Fint3	Fint4	Fnum	Fmph1	Fmph2	Fmph3	Fclc	Tint1	Tint2	Tint3	Tint4	Rto1	Rto2	Rto3	Okt	Tnum	Tmph1	Tmph2	Tmph3	Tclc	CellSize
21	1	100	0.951987179	2.617301744	5.216393075	0.568238087	0.867144588	7.47226127	8.712051113	7.937197981	3.155174381	0.286235709	0.059891364	0.539219783	0.879650774	0.787265408	0.566759575	0.288600911	1.48166248	1.871452091	1.32522882	3.867628437	-0.389867005	2.059423653	0.43058373
21	2	246	0.187824002	0.209436882	-0.394665483	0.437282141	-0.897187975	-0.355274584	1.131709595	0.752709182	-0.609812761	-0.34911173	-0.98650436	-0.74529152	-0.375646873	-0.634786194	0.447369388	-0.610175599	-0.409870548	-1.396076874	-0.225396489	0.495318745	-0.919209835	-0.530588237	-0.205914763
21	3	36	-1.176819882	-0.023514504	-0.22872729	0.214376152	-1.656658998	-0.861191029	-0.647568133	-0.318637483	-0.434512584	1.052052143	0.902862719	3.965456758	0.297188698	0.851521593	-0.302252636	-1.909062784	3.2669654	1.989485721	3.947867366	0.345461513	-1.024926929	-0.296073258	-0.158414352

SN: Slide Number; RN: Replicate Number; WN: Well Number

Experimental Data (Classification Assay):

CG11440 is not tested in classification assay

Integrated Annotations for CG11440 :

Gene Ontology Annoations: Biological Process

Biological Process - Term	GO ID	Evidence
dephosphorylation	GO:0016311	non-traceable author statement phototransduction

Gene Ontology Annoations: Cellular Component

Cellular Component - Term	GO ID	Evidence
membrane	GO:0016020	inferred from electronic annotation with InterPro:IPR000326

Gene Ontology Annoations: Molecular Function

Molecular Function - Term	GO ID	Evidence
phosphatidate phosphatase activity	GO:0008195	non-traceable author statement phosphatidate phosphatase activity

Other annotations

Database	Link
FlyBase	Click here to see CG11440 in FlyBase
FLIGHT	Click here to see CG11440 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRID	Click here to see CG11440 in BioGRID (Interaction Summary)
Off-target	Click here for Off-target data for CG11440
Entrez Gene	Entrez Gene page for CG11440
Uniprot	Uniprot page for CG11440

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Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)