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Gene Page - CG Number : CG11440
Gene Summary - CG11440:

CG11440: The gene lazaro is referred to in FlyBase by the symbol Dmel\laza (CG11440, FBgn0037163). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphatidate phosphatase activity. There is experimental evidence that it is involved in the biological process: response to light intensity; phototransduction; thermotaxis. 12 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; eye. It has one annotated transcript and one annotated polypeptide. Protein features are: Phosphatidic acid phosphatase type 2/haloperoxidase; Phosphatidic acid phosphatase/chloroperoxidase, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages.

Gene summary for CG11440 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11440:CG11440 is not perturbed in primary screen.
CG11440 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11440.
Cell Count:
CG_NumberCategoryR1R2R3
CG11440Primary screen526214130
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11440:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2111000.9519871792.6173017445.2163930750.5682380870.8671445887.472261278.7120511137.9371979813.1551743810.2862357090.0598913640.5392197830.8796507740.7872654080.5667595750.2886009111.481662481.8714520911.325228823.867628437-0.3898670052.0594236530.43058373
2122460.1878240020.209436882-0.3946654830.437282141-0.897187975-0.3552745841.1317095950.752709182-0.609812761-0.34911173-0.98650436-0.74529152-0.375646873-0.6347861940.447369388-0.610175599-0.409870548-1.396076874-0.2253964890.495318745-0.919209835-0.530588237-0.205914763
21336-1.176819882-0.023514504-0.228727290.214376152-1.656658998-0.861191029-0.647568133-0.318637483-0.4345125841.0520521430.9028627193.9654567580.2971886980.851521593-0.302252636-1.9090627843.26696541.9894857213.9478673660.345461513-1.024926929-0.296073258-0.158414352
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11440 is not tested in classification assay
Integrated Annotations for CG11440 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
dephosphorylationGO:0016311non-traceable author statement
phototransduction
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
membraneGO:0016020inferred from electronic annotation with InterPro:IPR000326
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
phosphatidate phosphatase activityGO:0008195non-traceable author statement
phosphatidate phosphatase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11440 in FlyBase
FLIGHTClick here to see CG11440 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11440 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11440
Entrez GeneEntrez Gene page for CG11440
UniprotUniprot page for CG11440

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)