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Gene Page - CG Number : CG11447
Gene Summary - CG11447:

CG11447: This gene is referred to in FlyBase by the symbol Dmel\CG11447 (FBgn0038737). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: rRNA (uridine-2'-O-)-methyltransferase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: RNA methylation. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Ribosomal RNA large subunit methyltransferase E; Ribosomal RNA methyltransferase FtsJ domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late pupal stages.

Gene summary for CG11447 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11447:CG11447 is not perturbed in primary screen.
CG11447 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11447.
Cell Count:
CG_NumberCategoryR1R2R3
CG11447Primary screen418123297
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11447:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2111020.001381887-0.0089319320.3285114860.1457778450.5353433154.1306982636.3714549173.7524431311.8729302560.002373440.5674375350.6334943850.1543063741.060629638-0.7094855190.123743077-0.3286669281.60117143-0.568580542.3264623890.737544942-0.187314972-0.653845916
212244-0.250318555-0.7928102050.342360251.333285398-1.385757787-0.308925263-0.359110784-0.682305286-0.975444411-1.058050415-1.753148418-0.029567961-1.655562327-1.3137228-0.674643868-0.7364387633.3414505672.9033295754.1179693220.2291501891.4542147571.405392966-0.914342338
213341.056519455-0.2635168890.3228462150.0897722010.2929945090.768033970.5338935190.9267451931.1106070121.1373634510.304649015-0.186870739-0.4951736270.405262665-0.220327338-0.739652219-0.694138876-0.356831782-0.0266786171.02062076-0.2121960361.127127813-0.482060252
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11447 is not tested in classification assay
Integrated Annotations for CG11447 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
RNA methylationGO:0001510inferred from electronic annotation with InterPro:IPR015507
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
rRNA (uridine-2'-O-)-methyltransferase activityGO:0008650inferred from sequence or structural similarity with InterPro:IPR002877
nucleic acid binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11447 in FlyBase
FLIGHTClick here to see CG11447 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11447 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11447
Entrez GeneEntrez Gene page for CG11447
UniprotUniprot page for CG11447

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)