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Gene Page - CG Number : CG11453
Gene Summary - CG11453:

CG11453: This gene is referred to in FlyBase by the symbol Dmel\CG11453 (FBgn0038734). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: 4-coumarate-CoA ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: metabolic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: AMP-binding, conserved site; AMP-dependent synthetase/ligase; Domain of unknown function DUF4009. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages.

Gene summary for CG11453 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11453:CG11453 is not perturbed in primary screen.
CG11453 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11453.
Cell Count:
CG_NumberCategoryR1R2R3
CG11453Primary screen47222362
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11453:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2111040.0429168890.4959351151.5422549851.5010494171.052897046.25909589.2964199847.8670808923.825482130.9739011643.3027095040.7222556131.0083052221.3667674660.3349601730.1649611281.6405567893.067945381.2475054454.8887431930.2841220464.1831891515.922961337
2122420.252939587-0.094188502-0.1173943420.267510884-0.5814904080.0006163031.7501306570.366070989-0.161632106-0.4385190651.1437187910.327606213-1.452269174-0.6095875430.651545643-0.872186475-0.338881928-0.482394573-0.2960363050.2037439761.7795383380.678508210.016674186
213323.8469487443.9606626360.9447471670.647624521-2.263616561-1.1904613630.784524724-1.132704298-3.4317026611.80336774-0.9497935331.9052065931.1347391490.1429566551.1539377290.2562271051.258376174-0.9185546472.3882074480.4156694142.28522387-0.2149491070.292794075
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11453 is not tested in classification assay
Integrated Annotations for CG11453 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
metabolic processGO:0008152inferred from electronic annotation with InterPro:IPR000873
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
4-coumarate-CoA ligase activityGO:0016207inferred from sequence or structural similarity with UniProtKB:O48869
Other annotations
DatabaseLink
FlyBaseClick here to see CG11453 in FlyBase
FLIGHTClick here to see CG11453 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11453 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11453
Entrez GeneEntrez Gene page for CG11453
UniprotUniprot page for CG11453

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)