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Gene Page - CG Number : CG1147
Gene Summary - CG1147:

CG1147: The gene neuropeptide F receptor is referred to in FlyBase by the symbol Dmel\NPFR1 (CG1147, FBgn0037408). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: neuropeptide F receptor activity. There is experimental evidence that it is involved in the biological process: larval feeding behavior. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: GPCR, rhodopsin-like; GPCR, rhodopsin-like, 7TM; Neuropeptide Y receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages.

Gene summary for CG1147 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1147:CG1147 is perturbed in following parameters in primary screen: Tclc
CG1147 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fint1+ LP_Fint2+ SP_Fint1+ SP_Fint2+ SP_Fint3+ SP_Fmph1+ SP_Fmph2+ SP_Fmph3+
CG1147 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1147.
Cell Count:
CG_NumberCategoryR1R2R3
CG1147Primary screen571960484
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1147:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG1147Slide8C0.2341.2301.0701.024
CG1147Slide8O0.1051.1731.1331.027
CG1147Slide8P0.0901.3801.0701.316
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG1147 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
G-protein coupled receptor signaling pathwayGO:0007186inferred from sequence or structural similarity
larval feeding behavior
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from sequence or structural similarity
integral to membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
neuropeptide F receptor activityGO:0042263non-traceable author statement
neuropeptide receptor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG1147 in FlyBase
FLIGHTClick here to see CG1147 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1147 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1147
Entrez GeneEntrez Gene page for CG1147
UniprotUniprot page for CG1147

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)