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Gene Page - CG Number : CG11490
Gene Summary - CG11490:

CG11490: This gene is referred to in FlyBase by the symbol Dmel\Tbc1d15-17 (CG11490, FBgn0031233). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTPase activator activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: regulation of Rab GTPase activity. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Rab-GTPase-TBC domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.

Gene summary for CG11490 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11490:CG11490 is not perturbed in primary screen.
CG11490 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11490.
Cell Count:
CG_NumberCategoryR1R2R3
CG11490Primary screen174562341
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11490:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211118-0.4271164820.0229162850.5173842270.652104874-0.8083220842.676338672.8333863940.929549052-1.04243357-1.691057702-0.742085999-0.879599838-1.2842210521.0245936430.234412235-1.132073144-0.513108535-1.815399686-1.300920747-1.0156086092.22166759-0.783710378-0.160310009
2122581.8480969462.410374852.366174541-0.4109865210.8952165113.9421566164.9970362844.1489427572.7558257330.6955406551.20547891-0.4667875241.0249361890.600644349-0.4821138691.0748664222.0046868020.5665670561.1269187763.45836993-0.3363113850.635113289-0.21610436
21348-0.677643858-0.099330161-0.070603763-0.3762230390.1754838881.349968650.5109308411.2258423441.409743655-0.7292770530.004105114-0.860862857-0.7094391620.428243939-0.62828426-0.464389181-0.506790317-0.2977610380.9079637721.0016320662.016352227-0.860502815-0.506893212
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11490 is not tested in classification assay
Integrated Annotations for CG11490 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
regulation of Rab GTPase activityGO:0032313inferred from electronic annotation with InterPro:IPR000195
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
intracellularGO:0005622inferred from electronic annotation with InterPro:IPR000195
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
GTPase activator activityGO:0005096inferred from sequence or structural similarity with SGD_LOCUS:GYP7; SGD:S0002393
Rab GTPase activator activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11490 in FlyBase
FLIGHTClick here to see CG11490 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11490 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11490
Entrez GeneEntrez Gene page for CG11490
UniprotUniprot page for CG11490

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)