Gene Page - CG Number : CG11505

Gene Summary - CG11505:

CG11505: This gene is referred to in FlyBase by the symbol Dmel\CG11505 (FBgn0035424). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: nucleic acid binding. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: RNA recognition motif domain; RNA-binding protein Lupus La; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG11505 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)

Experimental Summary - CG11505:

CG11505 is perturbed in following parameters in primary screen: Fmph1 Fmph2 Fmph3
CG11505 is perturbed in following parameters in classification assay (fluid): CellSize-(fld) LP_Fnum- NuCellD+(fld) NuSize-(fld) SP_Fnum-
CG11505 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Fint1+ Fint2+ NuCellD+(tfr) NuFluct+(tfr) Rto1+(tfr) Tint1+ Tint2+ Tmph2+ Tmph3+

Cellular phenotyping(Images):

Click here to access phenotyping images of gene CG11505.

Cell Count:

CG_Number	Category	R1	R2	R3
CG11505	Primary screen	109	551	337
CG11505	Secondary assay	899	1139	928

R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3

Primary screen data - CG11505:

SN	RN	WN	Fint1	Fint2	Fint3	Fint4	Fnum	Fmph1	Fmph2	Fmph3	Fclc	Tint1	Tint2	Tint3	Tint4	Rto1	Rto2	Rto3	Okt	Tnum	Tmph1	Tmph2	Tmph3	Tclc	CellSize
21	1	123	1.369248144	1.474901644	2.859557662	-1.213956251	-0.982737401	4.390961553	4.595110947	6.111141153	2.60191641	8.832282934	5.334117475	2.648359718	5.248587863	6.243581131	4.189922835	0.520259817	8.028910242	6.497745282	11.99248321	2.142548483	1.683969251	0.722529213	-1.107137223
21	2	283	0.738209901	0.993836988	1.96363512	1.277233639	0.757077245	4.562573856	5.915429934	5.230848158	2.837544907	0.355313926	2.101719508	2.460553745	1.422250725	1.46181635	1.498625871	-0.177226607	2.187126614	1.54908345	2.249453914	3.990533751	-0.286449461	3.751797322	1.376959038
21	3	13	-0.022804643	-0.778336746	-0.782392098	0.361905078	0.401674765	0.303584758	-0.260479467	0.439428849	1.097819982	-0.128895842	0.284060072	-0.157207906	-0.324903896	0.288063983	-0.945281756	-0.033332968	0.960921726	0.537315495	1.593366479	0.672715749	-0.042473957	2.000657997	0.649023037

SN: Slide Number; RN: Replicate Number; WN: Well Number

Experimental Data (Classification Assay):

Fluid:

CG_Number	Slide No.	ttest P-value	Ratio 1	Ratio 2	Ratio 3
CG11505	Slide10C	0.959	1.358	0.932	0.674
CG11505	Slide10O	0.102	1.256	1.081	1.099
CG11505	Slide10P	0.765	1.247	0.972	0.570

C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

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Transferrin:

CG_Number	Slide No.	ttest P-value	Ratio 1	Ratio 2	Ratio 3
CG11505	Slide10F	0.004	1.336	1.253	1.417
CG11505	Slide10O	0.532	0.877	1.018	0.997
CG11505	Slide10T	0.147	1.165	1.018	1.116

F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG11505 :

Gene Ontology Annoations: Biological Process

Biological Process - Term	GO ID	Evidence
biological_process	GO:0008150	no biological data available

Gene Ontology Annoations: Cellular Component

Cellular Component - Term	GO ID	Evidence
cellular_component	GO:0005575	no biological data available

Gene Ontology Annoations: Molecular Function

Molecular Function - Term	GO ID	Evidence
nucleic acid binding	GO:0003676	inferred from electronic annotation with InterPro:IPR000504

Other annotations

Database	Link
FlyBase	Click here to see CG11505 in FlyBase
FLIGHT	Click here to see CG11505 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRID	Click here to see CG11505 in BioGRID (Interaction Summary)
Off-target	Click here for Off-target data for CG11505
Entrez Gene	Entrez Gene page for CG11505
Uniprot	Uniprot page for CG11505

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Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)