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Gene Page - CG Number : CG11512
Gene Summary - CG11512:

CG11512: The gene Glutathione S transferase D4 is referred to in FlyBase by the symbol Dmel\GstD4 (CG11512, FBgn0010040). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: glutathione transferase activity. There is experimental evidence that it is involved in the biological process: glutathione metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Glutathione S-transferase/chloride channel, C-terminal; Thioredoxin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.

Gene summary for CG11512 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11512:CG11512 is perturbed in following parameters in primary screen: Fmph2
CG11512 is perturbed in following parameters in classification assay (fluid): NuCellD-(fld) NuCirc-(fld) NuSize+(fld) Rto2- SP_Fint4+
CG11512 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11512.
Cell Count:
CG_NumberCategoryR1R2R3
CG11512Primary screen580257221
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11512:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2111250.1019704822.8862133813.1509603140.5070983671.201735577.4718195177.6371160265.0479336372.8998218970.5832759170.4470273970.0429837820.442095030.8423926080.2333986920.4550013940.4403707770.686682825-0.1868632383.5001842940.2455466214.42679640.526537607
2122810.5743232160.2250202521.1164491680.813287412-0.7498798181.3281853253.7130663332.271153893-0.116363359-0.0625106320.3772863080.224422537-0.6260464130.181660769-0.162569747-0.537235742-0.522291901-0.422219423-0.7486255330.3795625630.131996792-0.103544388-0.191493281
21311-0.081419059-0.627975604-0.4641064590.579735816-0.687156342-0.1419545320.082767670.103827328-0.370288559-0.946317854-0.6720821760.072476286-0.8551895-0.552379407-0.486966352-0.970014374-0.592977142-0.407578778-0.5442843710.019497175-0.2495193120.778354594-0.598205158
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11512Slide20C0.7120.9031.1021.086
CG11512Slide20O0.8911.0950.7491.231
CG11512Slide20P0.1790.9560.9810.942
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11512 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
-
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
glutathione transferase activityGO:0004364inferred from sequence or structural similarity with MGD:Gstt1; MGI:MGI:107379
glutathione transferase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11512 in FlyBase
FLIGHTClick here to see CG11512 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11512 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11512
Entrez GeneEntrez Gene page for CG11512
UniprotUniprot page for CG11512

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)