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Gene Page - CG Number : CG11525
Gene Summary - CG11525:

CG11525: The gene Cyclin G is referred to in FlyBase by the symbol Dmel\CycG (CG11525, FBgn0039858). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: cyclin-dependent protein kinase regulator activity. There is experimental evidence that it is involved in the biological process: negative regulation of S phase of mitotic cell cycle; negative regulation of G1/S transition of mitotic cell cycle. 20 alleles are reported. The phenotypes of these alleles are annotated with: male genitalia; wing; ommatidium. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Cyclin, N-terminal; Cyclin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.

Gene summary for CG11525 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11525:CG11525 is not perturbed in primary screen.
CG11525 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11525.
Cell Count:
CG_NumberCategoryR1R2R3
CG11525Primary screen309155334
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11525:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211127-0.473754257-0.2791671390.586959981-0.060089888-0.096199268-0.3341771891.001593163-0.2876122160.091738018-0.1343324941.119289456-0.829426513-0.0178144380.80327348-0.429054831-0.147130302-0.2558661650.195423171-0.4591566380.6222100910.412274770.2948108180.241383402
2122790.080439093-0.0878381330.620899322-0.273999615-1.814770060.935701521-2.1878150140.679969395-5.320347287-1.282893327-0.9128326730.533635542.3297179642.122693196-0.896445533-0.407996247-0.978772691-2.945083829-1.030161373-4.233637698-0.321874381.792799363-0.860890651
2139-0.3456638420.1302708670.882381295-0.2066180320.1115590821.1123439091.3213288441.3221348531.348196287-0.492570243-0.383434024-0.189343503-0.939011773-0.592559695-0.2922808070.2344906270.27020551-0.9319866921.0881917792.232637340.75094977-0.519400233-0.43281113
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11525 is not tested in classification assay
Integrated Annotations for CG11525 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
negative regulation of G1/S transition of mitotic cell cycleGO:2000134inferred from genetic interaction with CycE
negative regulation of S phase of mitotic cell cycle
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
polytene chromosomeGO:0005700inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
cyclin-dependent protein kinase regulator activityGO:0016538inferred from sequence or structural similarity
cyclin-dependent protein kinase regulator activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11525 in FlyBase
FLIGHTClick here to see CG11525 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11525 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11525
Entrez GeneEntrez Gene page for CG11525
UniprotUniprot page for CG11525

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)