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Gene Page - CG Number : CG11567
Gene Summary - CG11567:

CG11567: The gene Cytochrome P450 reductase is referred to in FlyBase by the symbol Dmel\Cpr (CG11567, FBgn0015623). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: NADPH-hemoprotein reductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process. 15 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: FAD-binding, type 1; Ferredoxin reductase-type FAD-binding domain; Flavodoxin; Flavodoxin/nitric oxide synthase; Flavoprotein pyridine nucleotide cytochrome reductase; NADPH-cytochrome P450 reductase; NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3; Oxidoreductase FAD/NAD(P)-binding; Riboflavin synthase-like beta-barrel. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.

Gene summary for CG11567 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11567:CG11567 is not perturbed in primary screen.
CG11567 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11567.
Cell Count:
CG_NumberCategoryR1R2R3
CG11567Primary screen335140207
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11567:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211148-0.8456744010.1084947980.2223777620.0691124630.2086197790.3008173991.6164143060.287378060.032994269-0.25026050.417905563-0.3186556990.1706983420.856656445-0.697081899-0.2010452350.044438646-0.426604906-1.151656276-0.060575750.7267041490.2793222111.555900336
2122882.0487489011.11059812-0.85833197-0.112424832-1.8142407110.1878879251.4103272750.395337467-1.278769503-0.2741726290.21863459-1.125936452-0.522476162-0.031592421-0.510855522-1.5085931543.0893339-0.5027794940.444685797-0.3581660980.235926799-0.130778874-0.909108653
21318-0.724731384-0.053939294-0.091600541-0.371417089-0.7687037580.262878715-0.6026783970.423904071-1.454446259-1.007173364-0.289074587-0.703561827-1.0874251540.5635396690.504336657-0.422083229-0.814778386-0.923416731-0.412544127-1.03114162.44469063-0.482602257-0.294634456
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11567 is not tested in classification assay
Integrated Annotations for CG11567 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
oxidation-reduction processGO:0055114inferred from electronic annotation with InterPro:IPR001094, InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR003097, InterPro:IPR017927, InterPro:IPR017938, InterPro:IPR023173, InterPro:IPR023208
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
lipid particleGO:0005811inferred from direct assay
endoplasmic reticulum
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
NADPH-hemoprotein reductase activityGO:0003958inferred from sequence or structural similarity with UniProtKB:Q07994
NADPH-hemoprotein reductase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11567 in FlyBase
FLIGHTClick here to see CG11567 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11567 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11567
Entrez GeneEntrez Gene page for CG11567
UniprotUniprot page for CG11567

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)