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Gene Page - CG Number : CG11583
Gene Summary - CG11583:

CG11583: This gene is referred to in FlyBase by the symbol Dmel\CG11583 (FBgn0035524). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: neurogenesis. 4 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Anticodon-binding; Brix domain; Ribosome biogenesis protein BRX1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.

Gene summary for CG11583 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11583:CG11583 is not perturbed in primary screen.
CG11583 is not tested in classification assay (fluid).
CG11583 is perturbed in following parameters in classification assay (transferrin): Fint1+ NuFluct+(tfr) Tint1+ Tint4-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11583.
Cell Count:
CG_NumberCategoryR1R2R3
CG11583Primary screen251554185
CG11583Secondary assay803769549
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11583:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211154-0.913198215-0.5352727970.480852468-0.437530674-0.469816955-0.2738235221.065978819-0.531108439-0.7943957110.809330207-0.415253362-0.4646827210.6050524791.186938621-0.591144458-0.4156628480.1745769781.335737562-0.246090705-0.828747425-0.4352174940.1093712111.152953346
2121321.9429852731.216716211.6836021090.977042851.1599948741.3066594182.7623231311.4546761092.2869189480.8424318172.651407701-0.5881890970.5248503330.0970688520.1781014790.2712417591.905706831.7343730691.6370545843.103223494-0.0688305931.4420271341.236970571
213282-0.591249223-0.6296699272.754145204-0.583292061-0.4540653120.5962213060.6965057540.2602672481.3135150661.1954676010.8398391931.1959153710.119820006-0.4449054981.082357786-0.832864930.7427808882.6534914671.6758111571.655203216-0.845658973-0.522509022-1.027299619
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11583Slide10F0.0071.3881.4341.321
CG11583Slide10O0.8600.8701.0720.983
CG11583Slide10T0.2890.7690.9610.848
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG11583 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
ribosomal large subunit biogenesisGO:0042273inferred from sequence or structural similarity with UniProtKB:Q9VZE6
neurogenesis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleolusGO:0005730inferred from sequence or structural similarity with UniProtKB:Q9VZE6
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
-
Other annotations
DatabaseLink
FlyBaseClick here to see CG11583 in FlyBase
FLIGHTClick here to see CG11583 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11583 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11583
Entrez GeneEntrez Gene page for CG11583
UniprotUniprot page for CG11583

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)