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Gene Page - CG Number : CG11600
Gene Summary - CG11600:

CG11600: This gene is referred to in FlyBase by the symbol Dmel\CG11600 (FBgn0038068). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: triglyceride lipase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: lipid metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Alpha/beta hydrolase fold-1; Lipase, eukaryotic; Partial AB-hydrolase lipase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected. Peak expression observed in adult male stages.

Gene summary for CG11600 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11600:CG11600 is perturbed in following parameters in primary screen: NuSize
CG11600 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fmph1+ NuCirc-(fld) NuFluct+(fld) Okt+(fld) Rto3+ SP_Fmph1+
CG11600 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11600.
Cell Count:
CG_NumberCategoryR1R2R3
CG11600Primary screen481438170
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11600:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211168-0.7750864881.4297659610.1178334780.6084119850.6322659514.2818582036.833389165.4919877472.7375794540.649756541.9768525150.1148247260.796868410.614070092-0.179044525-0.018492791.235619242.099503642.1415172143.435388797-0.2910727033.7572581285.833052908
212148-0.922685371-0.2707569140.176105044-0.3004733460.1805294542.2873875741.7767264112.1907682651.542167190.1120671360.073836963-0.1887488050.003352332-0.1348008620.044077403-0.407677275-0.225354035-0.368733831-0.4039152721.5862251430.1787063944.434274152.17585225
2132980.2095546-0.904299596-0.604547333-0.393874204-0.587719975-0.495822412-0.770836906-0.168858142-1.2048909150.473620026-0.114322260.57267814-0.8585985770.5210926080.830919983-1.5687691221.9315904140.0560045551.292049826-1.1220826490.4849025070.276683297-0.286677791
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11600Slide8C0.6681.0520.9480.927
CG11600Slide8O0.0661.1581.4711.296
CG11600Slide8P0.7231.0910.9391.037
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11600 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
lipid metabolic processGO:0006629inferred from electronic annotation with InterPro:IPR006693
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
triglyceride lipase activityGO:0004806inferred from sequence or structural similarity with EMBL:Z31689; protein_id:CAA83494
Other annotations
DatabaseLink
FlyBaseClick here to see CG11600 in FlyBase
FLIGHTClick here to see CG11600 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11600 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11600
Entrez GeneEntrez Gene page for CG11600
UniprotUniprot page for CG11600

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)