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Gene Page - CG Number : CG11608
Gene Summary - CG11608:

CG11608: This gene is referred to in FlyBase by the symbol Dmel\CG11608 (FBgn0038069). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: triglyceride lipase activity. There is experimental evidence that it is involved in the biological process: multicellular organism reproduction. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Alpha/beta hydrolase fold-1; Lipase, eukaryotic; Partial AB-hydrolase lipase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed in adult male stages.

Gene summary for CG11608 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11608:CG11608 is perturbed in following parameters in primary screen: Fmph2
CG11608 is perturbed in following parameters in classification assay (fluid): LP_Fclc+ LP_Fint2+ LP_Fint3+ LP_Fint4- LP_Fmph1+ LP_Fmph2+ LP_Fmph3+ LP_Fnum+ NuCellD-(fld) NuCirc-(fld) NuFluct+(fld) NuSize+(fld) Okt-(fld) Rto2- Rto3- SP_Fclc+ SP_Fint1+ SP_Fint2+ SP_Fint3+
CG11608 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11608.
Cell Count:
CG_NumberCategoryR1R2R3
CG11608Primary screen5395510
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11608:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211173-0.261731089-0.103641104-0.123923770.1026103790.4512342993.6378749227.075475144.5010630032.7790120310.2372498881.1406844-0.15923140.5181639350.7806255232.0692274130.6289653332.2416762981.7554297431.5469172833.7567594031.203462590.4496908770.256156156
212143-0.0130701550.5331340641.652131850.596594535-0.0342970672.3093536574.6501262712.1788480442.046379101-0.8086765840.585106054-0.4479510080.151828764-0.16949422-0.6114725910.528634252-0.313981983-1.106299046-0.4886600022.3609744720.3691583632.1607891190.613871239
213293-5.025710707-4.356668827-4.6976324-5.144425496-6.41661632-7.330606185-5.295593391-7.238020104-13.77088076-5.100211759-5.224698715-5.53185451-6.646615384-5.565077529-5.399080283-5.545556225-5.629753328-5.004912221-5.986557669-10.58973991-4.950812238-4.279564057-3.81518551
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11608Slide20C0.0041.2861.4241.420
CG11608Slide20O0.0000.8330.8250.785
CG11608Slide20P0.0521.1381.2741.108
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11608 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
lipid metabolic processGO:0006629inferred from electronic annotation with InterPro:IPR006693
multicellular organism reproduction
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
extracellular spaceGO:0005615inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
triglyceride lipase activityGO:0004806inferred from sequence or structural similarity with EMBL:Z31689; protein_id:CAA83494
Other annotations
DatabaseLink
FlyBaseClick here to see CG11608 in FlyBase
FLIGHTClick here to see CG11608 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11608 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11608
Entrez GeneEntrez Gene page for CG11608
UniprotUniprot page for CG11608

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)