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Gene Page - CG Number : CG11622
Gene Summary - CG11622:

CG11622: The gene Ral interacting protein is referred to in FlyBase by the symbol Dmel\Rlip (CG11622, FBgn0026056). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; Ral GTPase binding. There is experimental evidence that it is involved in the biological process: receptor-mediated endocytosis. 8 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Rho GTPase activation protein; Rho GTPase-activating protein domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG11622 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11622:CG11622 is not perturbed in primary screen.
CG11622 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11622.
Cell Count:
CG_NumberCategoryR1R2R3
CG11622Primary screen384519178
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11622:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2111770.5736957281.5443993392.670508520.0050195220.1029467241.8420477886.2937952562.2427031660.8371901750.512796595-0.618673676-0.336049847-0.3144776260.118841186-0.771088590.392258455-0.418334642-0.392163193-0.6636772781.683789690.828949872.5507191991.789339821
2121390.2877312220.007586840.3480193780.0992472770.1176477211.6646692872.3883497411.651302642.325433753-0.43406241.3334169561.8560992040.422135817-0.0357928270.8606768420.405678783-0.0190112420.2091713660.3714819962.884236267-0.4696140872.7678246071.034015545
213289-1.010074183-0.6402300630.0823151270.295164566-0.411507561-0.092396771-0.0540478990.484431891-0.272424304-0.8892064590.1150772761.1778652990.89739822.1130601360.474816847-0.645976919-1.15217438-0.240339145-0.8813667160.0405757471.758566954-1.011631790.199209128
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11622 is not tested in classification assay
Integrated Annotations for CG11622 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
receptor-mediated endocytosisGO:0006898inferred from mutant phenotype
signal transduction
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
intracellularGO:0005622inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
Ral GTPase activator activityGO:0017123inferred from sequence or structural similarity with UniProtKB:Q62172
protein binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11622 in FlyBase
FLIGHTClick here to see CG11622 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11622 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11622
Entrez GeneEntrez Gene page for CG11622
UniprotUniprot page for CG11622

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)