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Gene Page - CG Number : CG11624
Gene Summary - CG11624:

CG11624: The gene Ubiquitin-63E is referred to in FlyBase by the symbol Dmel\Ubi-p63E (CG11624, FBgn0003943). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: cellular process; phagocytosis, engulfment. 11 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Ubiquitin; Ubiquitin conserved site; Ubiquitin subgroup; Ubiquitin supergroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.

Gene summary for CG11624 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11624:CG11624 is perturbed in following parameters in primary screen: Fint2 Tint3 Tmph1 Tmph2 Tmph3
CG11624 is perturbed in following parameters in classification assay (fluid): CellSize-(fld) LP_Fint1+ LP_Fint2+ LP_Fint4+ LP_Fmph2+ NuCellD+(fld) NuCirc+(fld) NuFluct-(fld) NuSize-(fld) Okt+(fld) Rto1- Rto2- SP_Fint2- SP_Fint3- SP_Fnum-
CG11624 is perturbed in following parameters in classification assay (transferrin): Fclc- Fint1- Fint2- Fint3- Fmph1- Fmph2- Fmph3- Fnum- NuCirc+(tfr) NuFluct-(tfr) NuSize-(tfr) Okt+(tfr) Rto1-(tfr) Rto2-(tfr) Rto3-(tfr) Tclc- Tint1- Tint2- Tint3- Tint4- Tmph1- Tmph2- Tmph3- Tnum-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11624.
Cell Count:
CG_NumberCategoryR1R2R3
CG11624Primary screen93869
CG11624Secondary assay719623480
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11624:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2111782.1257812064.3638969674.9380772222.439148573-0.3605912476.5109285028.37297205410.010200352.8096291883.6572614721.2058033971.161588354-1.0393299331.7627695210.459458085-1.1419775112.721397794.30701945-0.7367468222.4679013847.067579455-0.400383977-0.261352523
2121383.3477017824.0352153582.0041916881.809958477-2.2485334120.6623384511.8495666420.0219695295.7980072495.7219119292.1731395557.3326546796.0635229884.463641215-0.8481369390.3033714319.456110515.4948895366.9059083163.484624216-1.00092756-0.290241495-0.862258241
213288-1.6324577870.268847803-1.0508852561.651222153-3.435430576-3.44244149-3.186250189-1.6117267150.2184870890.825291912-0.3442290491.0055959051.8129646641.100403218-1.209492819-1.2701440474.3540232473.1190404675.315323334-2.181827317-1.983311028-1.478163749-0.278288864
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11624Slide10C0.3670.9730.9140.936
CG11624Slide10O0.0001.6801.7591.716
CG11624Slide10P0.0100.5630.6420.449
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse


Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11624Slide2F0.0020.7070.7090.786
CG11624Slide2O0.0001.4621.4941.487
CG11624Slide2T0.0000.2370.2610.220
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG11624 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
cellular processGO:0009987inferred from mutant phenotype
phagocytosis, engulfment
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
microtubule associated complexGO:0005875inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
-
Other annotations
DatabaseLink
FlyBaseClick here to see CG11624 in FlyBase
FLIGHTClick here to see CG11624 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11624 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11624
Entrez GeneEntrez Gene page for CG11624
UniprotUniprot page for CG11624

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)