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Gene Page - CG Number : CG11648
Gene Summary - CG11648:

CG11648: The gene Abdominal B is referred to in FlyBase by the symbol Dmel\Abd-B (CG11648, FBgn0000015). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: transcription regulatory region sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; RNA polymerase II distal enhancer sequence-specific DNA binding. There is experimental evidence for 18 unique biological process terms, many of which group under: anatomical structure development; organ development; biological regulation; multicellular organismal process; multicellular organismal reproductive process; open tracheal system development; organ morphogenesis; development of primary male sexual characteristics; regulation of multicellular organismal development; genital disc development. 210 alleles are reported. The phenotypes of these alleles are annotated with 109 unique terms, many of which group under: organ system subdivision; adult segment; organ system; abdominal ventral denticle belt; thoracic segment; spiracle; late extended germ band embryo; abdominal segment 7; embryonic abdomen; primordium. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Homeobox, conserved site; Homeodomain; Homeodomain, metazoa; Homeodomain-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis.

Gene summary for CG11648 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11648:CG11648 is not perturbed in primary screen.
CG11648 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11648.
Cell Count:
CG11648Primary screen241142154
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11648:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11648 is not tested in classification assay
Integrated Annotations for CG11648 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
germ cell migrationGO:0008354inferred from mutant phenotype
gonadal mesoderm development
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634non-traceable author statement
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700non-traceable author statement
sequence-specific DNA binding transcription factor activity
Other annotations
FlyBaseClick here to see CG11648 in FlyBase
FLIGHTClick here to see CG11648 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11648 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11648
Entrez GeneEntrez Gene page for CG11648
UniprotUniprot page for CG11648

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)