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Gene Page - CG Number : CG11654
Gene Summary - CG11654:

CG11654: The gene Adenosylhomocysteinase at 13 is referred to in FlyBase by the symbol Dmel\Ahcy13 (CG11654, FBgn0014455). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: adenosylhomocysteinase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: one-carbon metabolic process. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Adenosylhomocysteinase; S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.

Gene summary for CG11654 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11654:CG11654 is not perturbed in primary screen.
CG11654 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11654.
Cell Count:
CG_NumberCategoryR1R2R3
CG11654Primary screen250479108
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11654:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211188-0.0246078341.012515081.007138164-0.62685154-0.2201943891.6107080875.572841220.50672956-0.2876405330.236827249-0.015878450.768610687-0.3682385690.5782931672.342054594-0.631443753-0.3977614240.160881731-0.8989963280.4920767680.783193144-0.095672029-0.116688523
212981.4429729770.32591188-0.0812537711.214631074-0.0130319541.6243825252.5176389143.2705766172.3112454120.5600315022.5720256360.1774383690.8190426010.799593-0.467906135-0.2777881440.945063711.6498208970.6246481952.3261791750.647389381.1883994040.19412839
213248-0.549694565-1.0166557490.901104833-1.534040729-2.003499443-1.835103149-1.068852849-1.875390673-3.1663349690.531716503-0.4758037-1.211070073-0.6526113050.182903702-0.32397984-2.011894616-0.4005122911.405859130.82587894-2.082428236-0.934642289-0.104740158-0.648997955
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11654 is not tested in classification assay
Integrated Annotations for CG11654 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
one-carbon metabolic processGO:0006730inferred from electronic annotation with InterPro:IPR000043, InterPro:IPR020082
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
adenosylhomocysteinase activityGO:0004013inferred from sequence or structural similarity with EMBL:M61832; protein_id:AAA51682 AND inferred from sequence or structural similarity with EMBL:S57284; protein_id:AAB25906 AND inferred from sequence or structural similarity with EMBL:U18796
adenosylhomocysteinase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11654 in FlyBase
FLIGHTClick here to see CG11654 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11654 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11654
Entrez GeneEntrez Gene page for CG11654
UniprotUniprot page for CG11654

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)