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Gene Page - CG Number : CG11661
Gene Summary - CG11661:

CG11661: The gene Neural conserved at 73EF is referred to in FlyBase by the symbol Dmel\Nc73EF (CG11661, FBgn0010352). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: oxoglutarate dehydrogenase (succinyl-transferring) activity. Based on sequence similarity, it is predicted to be involved in the biological process: tricarboxylic acid cycle. 9 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 8 annotated transcripts and 8 annotated polypeptides. Protein features are: 2-oxoglutarate dehydrogenase, E1 component; Dehydrogenase, E1 component; Transketolase-like, pyrimidine-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.

Gene summary for CG11661 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11661:CG11661 is not perturbed in primary screen.
CG11661 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11661.
Cell Count:
CG_NumberCategoryR1R2R3
CG11661Primary screen315209236
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11661:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2111930.1069297540.6361613790.6761967370.627439506-0.1163622950.1922622370.4431176313.866938221-0.078803141-0.932458952-0.2058966870.330916687-0.564447824-0.755598951-0.350185007-0.252420377-1.355816610.274843316-0.860131389-0.347263169-0.573779745-0.6001086180.040505146
21293-1.114048738-0.575917018-0.5287680790.755483543-1.150236575-1.2930743480.004134036-1.600525505-2.941274687-0.025097036-1.4871785231.253881634-1.893511252-0.880056032-0.742186125-0.84408796-1.535115242-2.480053084-1.842431313-2.4045107910.480443430.306604560.184757568
213243-0.499820672-0.166613049-0.406019185-0.288085522-0.017305011-1.746725137-0.926068592-2.094243537-2.709108223-0.57912462-0.134179077-0.97707091.9317064150.065671169-0.020488694-0.719693802-0.413689667-0.784126122-0.907539592-1.83397395-0.096997692-0.288722614-0.495258644
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11661 is not tested in classification assay
Integrated Annotations for CG11661 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
tricarboxylic acid cycleGO:0006099inferred from sequence or structural similarity with UniProtKB:Q02218
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
mitochondrial oxoglutarate dehydrogenase complexGO:0009353inferred from sequence or structural similarity with UniProtKB:Q02218
microtubule associated complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
oxoglutarate dehydrogenase (succinyl-transferring) activityGO:0004591inferred from sequence or structural similarity with SGD_LOCUS:KGD1; SGD:S0001387 AND inferred from sequence or structural similarity with UniProtKB:Q02218
oxoglutarate dehydrogenase (succinyl-transferring) activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11661 in FlyBase
FLIGHTClick here to see CG11661 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11661 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11661
Entrez GeneEntrez Gene page for CG11661
UniprotUniprot page for CG11661

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)