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Gene Page - CG Number : CG1167
Gene Summary - CG1167:

CG1167: The gene Ras oncogene at 64B is referred to in FlyBase by the symbol Dmel\Ras64B (CG1167, FBgn0003206). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTPase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: GTP catabolic process; small GTPase mediated signal transduction. 29 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; histaminergic neuron; organ system; adult segment; thoracic segment; embryonic head; region of integument; embryonic tagma; adult. It has one annotated transcript and one annotated polypeptide. Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Ras type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 12-24 hour embryonic stages, during late larval stages.

Gene summary for CG1167 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1167:CG1167 is not perturbed in primary screen.
CG1167 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1167.
Cell Count:
CG_NumberCategoryR1R2R3
CG1167Primary screen321529632
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1167:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG1167 is not tested in classification assay
Integrated Annotations for CG1167 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
small GTPase mediated signal transductionGO:0007264inferred from electronic annotation with InterPro:IPR001806
GTP catabolic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
membraneGO:0016020inferred from electronic annotation with InterPro:IPR020849
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
GTPase activityGO:0003924inferred from sequence or structural similarity with UniProtKB:P62070
GDP binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG1167 in FlyBase
FLIGHTClick here to see CG1167 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1167 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1167
Entrez GeneEntrez Gene page for CG1167
UniprotUniprot page for CG1167

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)