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Gene Page - CG Number : CG11678
Gene Summary - CG11678:

CG11678: The gene Actin-related protein 6 is referred to in FlyBase by the symbol Dmel\Arp6 (CG11678, FBgn0011741). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: chromatin binding. Based on sequence similarity, it is predicted to be involved in the biological process: heterochromatin organization. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Actin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG11678 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11678:CG11678 is perturbed in following parameters in primary screen: Fmph1 Fmph2 Tclc
CG11678 is perturbed in following parameters in classification assay (fluid): LP_Fclc+ LP_Fint4- NuSize+(fld) Rto2- Rto3- SP_Fmph2+ SP_Fmph3+ SP_Fnum+
CG11678 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11678.
Cell Count:
CG_NumberCategoryR1R2R3
CG11678Primary screen434488168
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11678:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2111990.9973897533.5168201483.6096189620.3231294781.0461612824.3368582697.3802376395.3400515582.5298476131.4857877872.950633548-0.1630786580.9273493580.8185044970.714338352-0.2509150851.3455972742.9847540970.890271493.8671615110.4486143820.7345657171.08406643
212117-0.6069780640.1841494521.919484617-0.0196890210.2667578843.3548848434.6850004542.7759525023.1913312840.3353074653.0265829061.096614331.1892462681.1006700960.8887158880.3016337111.3380618253.9097490391.1290503764.044477961-0.1768353854.7736762341.405148806
213267-0.5394220480.797757555-0.2311622070.5697914-0.4702483280.010684515-0.340456470.016348341-1.224870042-1.161728894-1.442565347-0.123148565-0.561259458-0.7953758791.515502661-1.2185997741.1327922450.4239174970.558939908-1.379734327-1.120483012-0.0225860941.291227855
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11678Slide20C0.6600.8911.1691.180
CG11678Slide20O0.5871.1410.6340.874
CG11678Slide20P0.3530.7670.9460.897
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11678 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
cytoskeleton organizationGO:0007010inferred from sequence or structural similarity
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
actin filamentGO:0005884inferred from sequence or structural similarity
actin filament
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
structural constituent of cytoskeletonGO:0005200inferred from sequence or structural similarity
structural constituent of cytoskeleton
Other annotations
DatabaseLink
FlyBaseClick here to see CG11678 in FlyBase
FLIGHTClick here to see CG11678 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11678 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11678
Entrez GeneEntrez Gene page for CG11678
UniprotUniprot page for CG11678

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)