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Gene Page - CG Number : CG11709
Gene Summary - CG11709:

CG11709: The gene Peptidoglycan recognition protein SA is referred to in FlyBase by the symbol Dmel\PGRP-SA (CG11709, FBgn0030310). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; muramyl dipeptide binding; peptidoglycan binding. There is experimental evidence that it is involved in the biological process: defense response to Gram-positive bacterium; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria; response to peptidoglycan. 19 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: N-acetylmuramoyl-L-alanine amidase domain; Peptidoglycan recognition protein; Peptidoglycan recognition protein family domain, metazoa/bacteria; Peptidoglycan recognition protein, PGRP-S. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during early pupal stages.

Gene summary for CG11709 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11709:CG11709 is not perturbed in primary screen.
CG11709 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11709.
Cell Count:
CG11709Primary screen356509144
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11709:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11709 is not tested in classification assay
Integrated Annotations for CG11709 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
response to peptidoglycanGO:0032494inferred from mutant phenotype
detection of bacterium
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to plasma membraneGO:0005887non-traceable author statement
extracellular region
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein bindingGO:0005515inferred from physical interaction with GNBP1
muramyl dipeptide binding
Other annotations
FlyBaseClick here to see CG11709 in FlyBase
FLIGHTClick here to see CG11709 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11709 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11709
Entrez GeneEntrez Gene page for CG11709
UniprotUniprot page for CG11709

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)