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Gene Page - CG Number : CG11710
Gene Summary - CG11710:

CG11710: This gene is referred to in FlyBase by the symbol Dmel\CG11710 (FBgn0031115). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ligand-dependent nuclear receptor binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: regulation of transcription, DNA-dependent. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: ASCH domain; PUA-like domain; Zinc finger, C2HC5-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages.

Gene summary for CG11710 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11710:CG11710 is perturbed in following parameters in primary screen: Fmph2 Tclc
CG11710 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fclc- LP_Fmph2- LP_Fmph3- Okt+(fld)
CG11710 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11710.
Cell Count:
CG_NumberCategoryR1R2R3
CG11710Primary screen423466150
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11710:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211210-0.044082130.8511267750.683603701-0.5221989560.1196344072.6216424334.6483166332.6104098391.4591907920.159848596-0.444135738-0.5963531630.238917991.20865159-0.0209305180.295515552-1.100360217-0.590473325-0.9241829941.5915794910.0658791072.9103148522.143110381
2121063.7364531343.272214493.9708239860.3202168910.4084815663.2926162396.5156528532.9152758732.1586326880.9969782190.1967241830.0943110590.7482245570.3062390140.03926367-0.0140400540.471275361-0.017113113-0.3157195053.557407617-0.4899949213.1624923111.875687383
2132561.9533700131.4731468450.5689928321.705484898-0.391955712-1.54438155-1.2791220950.19591414520.0039501519.246994093.8667086181.5375653267.8323854316.3506915638.1490559614.64897984921.5869836314.818363319.843367797.7300721052.2501409132.4721118752.3193315
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11710Slide8C0.1130.8770.8970.658
CG11710Slide8O0.0121.3981.3571.554
CG11710Slide8P0.1820.9520.8690.639
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11710 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
regulation of transcription, DNA-dependentGO:0006355inferred from electronic annotation with InterPro:IPR009349
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from electronic annotation with InterPro:IPR009349
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ligand-dependent nuclear receptor bindingGO:0016922inferred from sequence or structural similarity with UniProtKB:Q15650
zinc ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11710 in FlyBase
FLIGHTClick here to see CG11710 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11710 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11710
Entrez GeneEntrez Gene page for CG11710
UniprotUniprot page for CG11710

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)