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Gene Page - CG Number : CG11759
Gene Summary - CG11759:

CG11759: The gene Kinesin associated protein 3 is referred to in FlyBase by the symbol Dmel\Kap3 (CG11759, FBgn0028421). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: establishment or maintenance of microtubule cytoskeleton polarity; sensory perception of sound; anterograde axon cargo transport; sensory perception of smell; nonmotile primary cilium assembly. 13 alleles are reported. The phenotypes of these alleles are annotated with: sensillum basiconicum of antennal segment 3; labellar taste bristle; sensillum trichodeum of antennal segment 3; cilium. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Armadillo-like helical; Armadillo-type fold; Kinesin-associated protein 3. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during early pupal stages, in adult female stages.

Gene summary for CG11759 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11759:CG11759 is not perturbed in primary screen.
CG11759 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11759.
Cell Count:
CG_NumberCategoryR1R2R3
CG11759Primary screen528331115
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11759:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2112240.6671137911.9945336611.865476317-0.0599829790.5097239623.6085501775.5726642723.2035227851.9185648360.4769117830.398092273-0.1361923050.849377930.9846622220.0964423730.7653719820.026978730.338423592-0.4276573422.39316436-0.7972433651.2455035511.360638835
21262-0.699897989-0.128060009-0.298646138-0.1657944160.1753255350.129666384-0.4190010270.0378080860.0169257521.675865145-0.241616180.0049544060.5697426970.2636402860.224862836-0.2172400791.621865551.8082114951.2097788971.022711088-0.342705456-0.314115670.595170613
2132121.4258270940.3881002190.786647303-0.497220751-0.408591849-0.669550238-1.074518884-1.137050501-3.29767751-1.032862257-1.5950991180.020042959-0.6641644210.866727423-0.633412623-0.738760173-0.349960058-0.7593083120.187363712-2.4536741061.560417794-0.786859848-0.139145198
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11759 is not tested in classification assay
Integrated Annotations for CG11759 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
microtubule-based movementGO:0007018inferred from sequence or structural similarity with NCBI_gi:861365
sperm axoneme assembly
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
kinesin complexGO:0005871inferred from sequence or structural similarity with NCBI_gi:861365
kinesin II complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
microtubule motor activityGO:0003777inferred from sequence or structural similarity with NCBI_gi:861365
protein binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11759 in FlyBase
FLIGHTClick here to see CG11759 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11759 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11759
Entrez GeneEntrez Gene page for CG11759
UniprotUniprot page for CG11759

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)