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Gene Page - CG Number : CG11761
Gene Summary - CG11761:

CG11761: The gene translin is referred to in FlyBase by the symbol Dmel\trsn (CG11761, FBgn0033528). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: endoribonuclease activity. There is experimental evidence that it is involved in the biological process: RNA interference; protein stabilization; jump response. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Translin; Translin, C-terminal; Translin, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG11761 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11761:CG11761 is not perturbed in primary screen.
CG11761 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11761.
Cell Count:
CG_NumberCategoryR1R2R3
CG11761Primary screen196228107
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11761:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2112250.715839774-0.012182581-0.6545707122.420700365-0.5636444080.0556294331.1706852240.333795745-0.6563459770.9510092490.109004587-0.438943017-0.795189079-0.112453326-0.172506769-1.097378158-0.312259988-0.76627461-1.013441994-0.753060523-0.0551680060.056472042-0.256459488
212611.8525275480.460899918-0.1626815721.777172997-0.643240345-0.4472322871.379825063-0.111276458-0.663242933-1.733145405-0.555377368-0.539850819-2.439332837-0.348136590.849538841-0.830175486-1.5972957-1.558802978-0.568212956-0.033575188-0.849230239-0.8625562141.220137166
213211-0.808908586-0.4590519280.790311019-0.282250732-1.806135968-2.627273931-1.295432158-2.206141548-5.874798972-0.215497831-1.498821808-1.2680725660.76172434-0.2052497831.884043314-1.1956163160.271457839-1.4661468891.032417761-4.3042308230.344108619-1.1861698270.605365894
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11761 is not tested in classification assay
Integrated Annotations for CG11761 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
RNA interferenceGO:0016246inferred from mutant phenotype
protein stabilization
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from sequence or structural similarity with MGD:Tsn; MGI:MGI:109263
cytoplasm
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
DNA bindingGO:0003677inferred from sequence or structural similarity with UniProtKB:Q62348
endoribonuclease activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11761 in FlyBase
FLIGHTClick here to see CG11761 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11761 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11761
Entrez GeneEntrez Gene page for CG11761
UniprotUniprot page for CG11761

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)