Gene Page - CG Number : CG11779

Gene Summary - CG11779:

CG11779: This gene is referred to in FlyBase by the symbol Dmel\CG11779 (FBgn0038683). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: P-P-bond-hydrolysis-driven protein transmembrane transporter activity. There is experimental evidence that it is involved in the biological process: cellular response to hypoxia. 14 alleles are reported. The phenotypes of these alleles are annotated with: eye; trichogen cell; mesothoracic tergum. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Membrane transporter, Tim44-related/Ribosomal protein L45; Mitochondrial inner membrane translocase complex, subunit Tim44. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed in adult male stages.

Gene summary for CG11779 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)

Experimental Summary - CG11779:

CG11779 is not perturbed in primary screen.
CG11779 is not tested in classification assay.

Cellular phenotyping(Images):

Click here to access phenotyping images of gene CG11779.

Cell Count:

CG_Number	Category	R1	R2	R3
CG11779	Primary screen	516	168	174

R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3

Primary screen data - CG11779:

SN	RN	WN	Fint1	Fint2	Fint3	Fint4	Fnum	Fmph1	Fmph2	Fmph3	Fclc	Tint1	Tint2	Tint3	Tint4	Rto1	Rto2	Rto3	Okt	Tnum	Tmph1	Tmph2	Tmph3	Tclc	CellSize
21	1	230	-0.553443189	-0.613965854	0.074325229	0.271986503	0.320245418	2.633536141	4.131584384	2.613621238	2.310180536	0.155017639	2.465954283	-0.50695555	0.409624884	0.271763802	-0.174418104	0.315186355	0.647270195	1.559650017	0.897217749	2.09260943	-0.174330584	0.444689486	-0.183735597
21	2	86	1.375162755	0.449715263	0.673791658	0.003769996	-1.110135138	-0.356210904	1.331387208	-0.14760612	-1.526078406	-0.618312525	-0.687159872	-0.473992794	-0.800374582	-0.198555175	-0.693294852	-1.107629346	-1.165223457	-1.532577026	-1.419760585	-0.857988846	-0.727650074	0.143708173	-1.190969689
21	3	236	0.682009543	-0.584559256	-0.95548248	-0.679175198	-0.699101085	-1.167258468	-1.357812573	-1.234399333	-1.72949624	0.371656443	-0.587501312	0.649812491	-0.386523392	0.283547713	0.940202073	-1.030801848	-0.469648827	0.518926938	-0.57123212	-1.386258745	-0.06237906	-0.90033834	0.654971815

SN: Slide Number; RN: Replicate Number; WN: Well Number

Experimental Data (Classification Assay):

CG11779 is not tested in classification assay

Integrated Annotations for CG11779 :

Gene Ontology Annoations: Biological Process

Biological Process - Term	GO ID	Evidence
protein transport	GO:0015031	inferred from sequence or structural similarity with EMBL:U69898 protein targeting to mitochondrion

Gene Ontology Annoations: Cellular Component

Cellular Component - Term	GO ID	Evidence
mitochondrial inner membrane presequence translocase complex	GO:0005744	inferred from sequence or structural similarity with EMBL:U69898 mitochondrial inner membrane presequence translocase complex

Gene Ontology Annoations: Molecular Function

Molecular Function - Term	GO ID	Evidence
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	GO:0015450	inferred from sequence or structural similarity with EMBL:U69898 P-P-bond-hydrolysis-driven protein transmembrane transporter activity

Other annotations

Database	Link
FlyBase	Click here to see CG11779 in FlyBase
FLIGHT	Click here to see CG11779 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRID	Click here to see CG11779 in BioGRID (Interaction Summary)
Off-target	Click here for Off-target data for CG11779
Entrez Gene	Entrez Gene page for CG11779
Uniprot	Uniprot page for CG11779

---

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)