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Gene Page - CG Number : CG11796
Gene Summary - CG11796:

CG11796: This gene is referred to in FlyBase by the symbol Dmel\CG11796 (FBgn0036992). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: 4-hydroxyphenylpyruvate dioxygenase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process; aromatic amino acid family metabolic process. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: 4-hydroxyphenylpyruvate dioxygenase; Glyoxalase/fosfomycin resistance/dioxygenase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed during early larval stages, in adult male stages.

Gene summary for CG11796 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11796:CG11796 is perturbed in following parameters in primary screen: Fmph2 Fmph3
CG11796 is perturbed in following parameters in classification assay (fluid): NuCirc-(fld) Okt-(fld) SP_Fint3-
CG11796 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11796.
Cell Count:
CG_NumberCategoryR1R2R3
CG11796Primary screen433350294
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11796:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211237-0.7086157090.055074172-0.1441582560.071865690.2079285852.4341800434.6137810143.7251868731.4169608660.6942000790.640077598-0.0777744730.3047176770.9993822380.6412715070.422353898-0.7215088050.090622057-0.6069648371.6801631690.287262871.6989890690.307059944
21279-0.3910586741.1441642670.7405274620.3269413640.1797769963.4904429694.7392909534.4038178271.6901585450.4980667150.517379663-0.208154584-0.535353972-0.1478572890.3503564050.0412242381.4753581281.036861895-0.2587025093.0378406950.054340518-0.698599036-0.846511478
2132291.0227157690.4568804321.253710334-0.3918525790.1600330990.6883932581.0396273531.0620828610.8987379361.554328488-1.041793433-0.2363292050.6946113850.0193507560.129002171-0.0104274680.015637227-0.9248349261.4854704020.7497789991.078372815-0.510544508-0.755013019
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11796Slide20C0.5311.1920.5260.846
CG11796Slide20O0.0090.2990.1700.485
CG11796Slide20P0.0900.5860.6050.898
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11796 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
oxidation-reduction processGO:0055114inferred from electronic annotation with InterPro:IPR005956
aromatic amino acid family metabolic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
4-hydroxyphenylpyruvate dioxygenase activityGO:0003868inferred from sequence or structural similarity with UniProtKB:Q02110 AND inferred from sequence or structural similarity with UniProt:Q22633
Other annotations
DatabaseLink
FlyBaseClick here to see CG11796 in FlyBase
FLIGHTClick here to see CG11796 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11796 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11796
Entrez GeneEntrez Gene page for CG11796
UniprotUniprot page for CG11796

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)