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Gene Page - CG Number : CG11822
Gene Summary - CG11822:

CG11822: The gene nicotinic acetylcholine receptor beta 21C is referred to in FlyBase by the symbol Dmel\nAcR╬▓-21C (CG11822, FBgn0031261). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: acetylcholine-activated cation-selective channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ion transport. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding; Neurotransmitter-gated ion-channel transmembrane domain; Nicotinic acetylcholine receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages, during late pupal stages, in adult male stages.

Gene summary for CG11822 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11822:CG11822 is not perturbed in primary screen.
CG11822 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11822.
Cell Count:
CG11822Primary screen223326547
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11822:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11822 is not tested in classification assay
Integrated Annotations for CG11822 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
ion transportGO:0006811inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR006029, InterPro:IPR006201
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
acetylcholine-gated channel complexGO:0005892inferred from sequence or structural similarity
acetylcholine-gated channel complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
acetylcholine-activated cation-selective channel activityGO:0004889inferred from sequence or structural similarity
acetylcholine-activated cation-selective channel activity
Other annotations
FlyBaseClick here to see CG11822 in FlyBase
FLIGHTClick here to see CG11822 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11822 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11822
Entrez GeneEntrez Gene page for CG11822
UniprotUniprot page for CG11822

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)