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Gene Page - CG Number : CG11828
Gene Summary - CG11828:

CG11828: This gene is referred to in FlyBase by the symbol Dmel\CG11828 (FBgn0039616). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: procollagen-proline 4-dioxygenase activity. Based on sequence similarity, it is predicted to be involved in the biological process: peptidyl-proline hydroxylation to 4-hydroxy-L-proline. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Prolyl 4-hydroxylase alpha-subunit, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed in adult male stages.

Gene summary for CG11828 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11828:CG11828 is not perturbed in primary screen.
CG11828 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11828.
Cell Count:
CG11828Primary screen2373148
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11828:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11828 is not tested in classification assay
Integrated Annotations for CG11828 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
peptidyl-proline hydroxylation to 4-hydroxy-L-prolineGO:0018401inferred from sequence or structural similarity with MGD:P4ha1; MGI:MGI:97463
oxidation-reduction process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
procollagen-proline 4-dioxygenase complexGO:0016222inferred by curator from GO:0004656|GO:0018401
endoplasmic reticulum
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
procollagen-proline 4-dioxygenase activityGO:0004656inferred from sequence or structural similarity with MGD:P4ha1; MGI:MGI:97463
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Other annotations
FlyBaseClick here to see CG11828 in FlyBase
FLIGHTClick here to see CG11828 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11828 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11828
Entrez GeneEntrez Gene page for CG11828
UniprotUniprot page for CG11828

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)