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Gene Page - CG Number : CG11837
Gene Summary - CG11837:

CG11837: This gene is referred to in FlyBase by the symbol Dmel\CG11837 (FBgn0039627). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: rRNA (adenine-N6,N6-)-dimethyltransferase activity. There is experimental evidence that it is involved in the biological process: neurogenesis. 2 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: 18S rRNA dimethylase DIM1; Ribosomal RNA adenine dimethylase; Ribosomal RNA adenine methylase transferase; Ribosomal RNA adenine methylase transferase, N-terminal; Ribosomal RNA adenine methylase transferase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.

Gene summary for CG11837 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11837:CG11837 is not perturbed in primary screen.
CG11837 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11837.
Cell Count:
CG_NumberCategoryR1R2R3
CG11837Primary screen309524313
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11837:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2112570.334170343-0.175339007-0.646628295-0.453785118-0.113848411.2589406283.6014646461.3286203120.039702833-1.35007803-1.329831811-0.458401171-0.340709936-0.753217906-0.2555359110.139830504-1.84000309-1.486763153-1.8849256970.4530714360.676983613-0.022994382-0.576784471
212590.456770703-0.561896006-0.6085413930.6394092640.97675897-0.165018921-0.624415949-0.5114262971.1010593241.1189128070.626000792-0.0064244940.2870151470.7000126891.3607969070.326421790.9769750170.0500044360.7882545241.027867464-0.6861603782.5650400081.418614471
213209-0.506692271-0.3639665460.23225615-0.815195885-0.0791305730.9111859330.0465834061.1299678961.605895068-0.0047274420.818839189-0.3980423430.5794728860.443708848-0.872005171-0.2577869610.072036070.5364482040.3338752691.705988899-0.832385341-0.7225924850.034880084
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11837 is not tested in classification assay
Integrated Annotations for CG11837 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
rRNA modificationGO:0000154inferred from sequence or structural similarity with UniProtKB:P41819
neurogenesis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cellular_componentGO:0005575no biological data available
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
rRNA (adenine-N6,N6-)-dimethyltransferase activityGO:0000179inferred from sequence or structural similarity with SGD_LOCUS:DIM1; SGD:S0006187
rRNA (adenine-N6,N6-)-dimethyltransferase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11837 in FlyBase
FLIGHTClick here to see CG11837 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11837 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11837
Entrez GeneEntrez Gene page for CG11837
UniprotUniprot page for CG11837

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)