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Gene Page - CG Number : CG11848
Gene Summary - CG11848:

CG11848: The gene Band4.1 inhibitor LRP interactor is referred to in FlyBase by the symbol Dmel\Bili (CG11848, FBgn0039282). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: regulation of establishment of protein localization; negative regulation of Wnt receptor signaling pathway. 9 alleles are reported. The phenotype of these alleles is annotated with: embryonic/first instar larval cuticle. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Band 4.1 domain; FERM central domain; FERM domain; FERM/acyl-CoA-binding protein, 3-helical bundle. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages.

Gene summary for CG11848 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11848:CG11848 is perturbed in following parameters in primary screen: Fmph1 Fmph2 Fmph3 Tclc
CG11848 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fint1+ LP_Fmph2- Okt+(fld) SP_Fclc- SP_Fint1+
CG11848 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11848.
Cell Count:
CG_NumberCategoryR1R2R3
CG11848Primary screen595377378
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11848:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2112680.889479276-0.3825369110.6480261930.7264885851.1686763944.8244385027.9266701045.2640357942.8933156372.2883549990.9400092610.1057681451.4275889532.306835778-0.0696874720.4087538042.2202029681.039561331.7825523614.3821977040.2521157515.444993184.025801816
212480.4238334810.1001875120.6524514770.6676804350.8258935585.2269514816.3292456356.1826569812.7498321630.9250462243.3394975561.2498418381.9944963571.302586394-0.327086059-0.179088353.5423940082.8492301910.9131709773.7718807291.5394327681.4662311861.073514724
213198-0.496870328-0.566650746-0.0743732210.1616149960.8700265311.6200971760.5784015931.7120823011.611129532-0.597393816-0.8767800590.073372335-0.588440556-0.293106562-0.403320440.3824742060.063933404-0.851591219-0.5534385511.131742862-0.5482446890.896560048-0.006175985
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11848Slide8C0.1400.8600.9180.981
CG11848Slide8O0.0151.3111.1611.306
CG11848Slide8P0.4170.8710.9151.048
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11848 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
negative regulation of Wnt receptor signaling pathwayGO:0030178inferred from mutant phenotype
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoskeletonGO:0005856inferred from electronic annotation with InterPro:IPR000299
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
bindingGO:0005488inferred from electronic annotation with InterPro:IPR014352
Other annotations
DatabaseLink
FlyBaseClick here to see CG11848 in FlyBase
FLIGHTClick here to see CG11848 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11848 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11848
Entrez GeneEntrez Gene page for CG11848
UniprotUniprot page for CG11848

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)