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Gene Page - CG Number : CG11887
Gene Summary - CG11887:

CG11887: The gene Elongator complex protein 2 is referred to in FlyBase by the symbol Dmel\Elp2 (CG11887, FBgn0033540). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: endopeptidase activator activity. Based on sequence similarity, it is predicted to be involved in the biological process: proteasome assembly; transcription elongation from RNA polymerase II promoter. 5 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Quinonprotein alcohol dehydrogenase-like; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.

Gene summary for CG11887 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11887:CG11887 is not perturbed in primary screen.
CG11887 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11887.
Cell Count:
CG_NumberCategoryR1R2R3
CG11887Primary screen142245231
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11887:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211288-0.2077857180.8876073543.046004958-1.09699558-0.8423648880.1071663022.609051085-0.223472709-1.367419268-1.076775132-1.355569828-0.2977871970.405994588-0.209535675-0.107792973-1.081198711-2.569817561-2.054652707-1.882552357-1.7193957710.9332360540.709625776-0.14369484
212281.0043382940.143779826-0.1931816970.568622112-0.629174041-0.7794239920.747751942-0.476023809-0.601867885-1.007419492-0.4625966930.507432825-1.348830977-0.8110477390.680440907-0.464691051-1.71673073-0.958846725-1.925692293-0.1826332170.5753005561.278811219-0.365996978
213178-0.329599411-0.526068672-0.530903851-0.4019840770.174870614-0.538567886-1.397850755-1.13408184-2.648464166-0.234705769-0.696496557-1.006384395-0.0541258-0.269650783-0.5029069860.2890966340.559637454-1.2815873240.316581429-2.272927030.9214144110.404579109-0.533645776
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11887 is not tested in classification assay
Integrated Annotations for CG11887 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transcription elongation from RNA polymerase II promoterGO:0006368inferred from sequence or structural similarity with UniProtKB:Q16186
proteasome assembly
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
proteasome complexGO:0000502inferred from sequence or structural similarity with UniProtKB:Q16186
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
endopeptidase activator activityGO:0061133inferred from sequence or structural similarity with UniProtKB:Q16186
Other annotations
DatabaseLink
FlyBaseClick here to see CG11887 in FlyBase
FLIGHTClick here to see CG11887 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11887 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11887
Entrez GeneEntrez Gene page for CG11887
UniprotUniprot page for CG11887

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)