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Gene Page - CG Number : CG11896
Gene Summary - CG11896:

CG11896: The gene mann-cup is referred to in FlyBase by the symbol Dmel\m-cup (CG11896, FBgn0038488). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ubiquitin-protein ligase activity. Based on sequence similarity, it is predicted to be involved in the biological process: protein ubiquitination. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late pupal stages, in adult male stages.

Gene summary for CG11896 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11896:CG11896 is not perturbed in primary screen.
CG11896 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11896.
Cell Count:
CG_NumberCategoryR1R2R3
CG11896Primary screen308273321
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11896:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2112910.694199616-0.565963293-0.002090857-0.1069492110.0480021460.3193329620.6570534820.145475275-0.1515891490.638632004-0.6315143570.643643831-0.194747474-1.220158014-0.117542546-0.07576797-1.095378411-0.954375912-1.5629114860.480965055-0.591405343-0.196336087-0.567409802
21225-0.429961248-0.74030094-0.90843896-0.669430796-0.5519533332.0696927852.8371172922.067383850.639101393-0.5098611630.59865616-0.106843141-1.004330645-0.438456302-1.137029827-0.996877667-0.2257068090.06062092-0.2689335691.33887511-0.079120271-0.002908103-0.351807811
213175-0.502891522-0.5523867270.012005605-0.4896203990.1795939850.612298695-0.2333283570.6603863171.000086082-0.7048612260.9890602090.9886348490.3453120440.879031017-0.44674148-0.099148739-0.087456242-0.760609411-0.0415641960.141621771-0.614581869-0.512228783-0.481253807
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11896 is not tested in classification assay
Integrated Annotations for CG11896 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
protein ubiquitinationGO:0016567inferred from sequence or structural similarity with HGNC_gene:FEM1B; HGNC:3649
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cellular_componentGO:0005575no biological data available
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ubiquitin-protein ligase activityGO:0004842inferred from sequence or structural similarity with HGNC_gene:FEM1B; HGNC:3649
Other annotations
DatabaseLink
FlyBaseClick here to see CG11896 in FlyBase
FLIGHTClick here to see CG11896 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11896 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11896
Entrez GeneEntrez Gene page for CG11896
UniprotUniprot page for CG11896

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)