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Gene Page - CG Number : CG11898
Gene Summary - CG11898:

CG11898: This gene is referred to in FlyBase by the symbol Dmel\CG11898 (FBgn0039645). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: xenobiotic-transporting ATPase activity; drug transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter, integral membrane type 1; ABC transporter, transmembrane domain; ABC transporter, transmembrane domain, type 1; ABC transporter-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected. Peak expression observed within 18-24 hour embryonic stages, during late larval stages, in stages of adults of both sexes.

Gene summary for CG11898 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11898:CG11898 is perturbed in following parameters in primary screen: Fmph2
CG11898 is not perturbed in classification assay (fluid).
CG11898 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11898.
Cell Count:
CG_NumberCategoryR1R2R3
CG11898Primary screen556519238
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11898:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211293-0.0424356460.7180631080.5781725292.155663610.5800188882.0576302173.643100412.5726500612.5715171680.426150921.649829022-0.3375638750.8603398541.2342191460.5136337020.3028546340.66004490.7801433910.2431661812.5699840170.9162956643.3027647231.894559171
21223-0.601769686-0.1574345190.1980389680.8764846760.3911233533.5758770983.8748030313.6637710032.9363175241.5808029243.9522171491.4295306151.3511508020.989840744-0.064918555-0.0539111942.0541535231.8967165161.0950008023.5540119491.1411602630.6713331660.27635315
2131730.5647283781.4645483391.262273254-0.4304907430.1020677330.4509355210.5679123680.5853387960.34334273-0.339121805-0.9102339452.1730573591.4421683582.014249522-0.3086091730.2478408430.155854947-1.3497661760.8382187910.2394784321.6879701712.478641511-0.452319177
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11898Slide21C0.7951.4250.1060.000
CG11898Slide21O0.9571.7690.1180.000
CG11898Slide21P0.8191.5160.0420.000
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11898 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transmembrane transportGO:0055085inferred from electronic annotation with InterPro:IPR001140, InterPro:IPR011527
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from electronic annotation with InterPro:IPR001140, InterPro:IPR011527
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
xenobiotic-transporting ATPase activityGO:0008559inferred from sequence or structural similarity with UniProtKB:P39109
drug transmembrane transporter activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11898 in FlyBase
FLIGHTClick here to see CG11898 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11898 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11898
Entrez GeneEntrez Gene page for CG11898
UniprotUniprot page for CG11898

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)