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Gene Page - CG Number : CG11899
Gene Summary - CG11899:

CG11899: This gene is referred to in FlyBase by the symbol Dmel\CG11899 (FBgn0014427). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: O-phospho-L-serine:2-oxoglutarate aminotransferase activity. It is reported to be involved in the biological process: pyridoxine biosynthetic process; L-serine biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Aminotransferase class-V pyridoxal-phosphate binding site; Aminotransferase, class V/Cysteine desulfurase; Phosphoserine aminotransferase; Phosphoserine aminotransferase, subgroup; Pyridoxal phosphate-dependent transferase, major domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed during late larval stages, at stages throughout the pupal period.

Gene summary for CG11899 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11899:CG11899 is not perturbed in primary screen.
CG11899 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11899.
Cell Count:
CG_NumberCategoryR1R2R3
CG11899Primary screen427463170
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11899:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211294-0.94329219-0.387564013-0.4447655110.0834022820.2873340242.4697372762.3883885651.503875581.4227150341.2995614790.7419610190.446732211.0486218650.712001584-0.2190086540.1485641232.5998335451.1633634191.4045025471.382491703-0.500583067-0.201459519-0.433627939
21222-0.786704744-0.615191630.0349174090.7514027360.504178171.12465241.3205549711.9063092841.3356644931.3338047450.907717675-0.6801145770.2537127050.1214130950.1203074710.9398213631.2369639430.2881393080.5472065251.553443064-0.123745751.149329190.123995715
2131720.9936874670.609623637-0.44860106-0.953198289-0.496812564-0.2552865690.539598969-0.10596225-0.851448609-0.333908009-0.40716192-0.255697677-0.151902749-1.3478151790.885845599-0.66255502-1.14407452-0.100247225-0.720114794-0.3716263321.168297661-0.3128913160.677504634
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11899 is not tested in classification assay
Integrated Annotations for CG11899 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
L-serine biosynthetic processGO:0006564non-traceable author statement
pyridoxine biosynthetic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
O-phospho-L-serine:2-oxoglutarate aminotransferase activityGO:0004648inferred from sequence or structural similarity
O-phospho-L-serine:2-oxoglutarate aminotransferase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11899 in FlyBase
FLIGHTClick here to see CG11899 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11899 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11899
Entrez GeneEntrez Gene page for CG11899
UniprotUniprot page for CG11899

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)