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Gene Page - CG Number : CG11900
Gene Summary - CG11900:

CG11900: The gene Metazoan SpoT homolog-1 is referred to in FlyBase by the symbol Dmel\Mesh1 (CG11900, FBgn0039650). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity. There is experimental evidence that it is involved in the biological process: response to starvation; guanosine tetraphosphate catabolic process. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: (p)ppGpp synthetase; HD domain; HD/PDEase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in adult female stages.

Gene summary for CG11900 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11900:CG11900 is not perturbed in primary screen.
CG11900 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11900.
Cell Count:
CG_NumberCategoryR1R2R3
CG11900Primary screen188756279
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11900:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2112950.7913440880.209089307-1.034220489-0.306680995-0.847562553-0.815270854-0.433939838-0.521180773-1.935536752-0.27468053-0.868595977-0.1874725061.394708669-0.885118648-0.160817732-0.874297691-1.132488984-1.472474459-0.767067394-1.866630949-0.691368977-0.31046882.016813536
21221-0.469308057-0.3817424390.0664465481.2223946340.6436898582.9112153643.1284627522.9612188782.9420146090.2289052041.2198434120.1025553781.6097574950.979921603-0.3670031621.5889010031.1412491380.5083059190.9923963283.198525920.8029070552.831989881.903865513
2131710.6809779080.2736233910.1214034561.727306206-0.2617982641.0844081260.1346452630.8227879212.4685492261.8262016550.7731897230.3653591391.3564743121.2355919390.089874165-0.8504168150.8733681252.9405337521.6279546410.903625265-0.5079747252.3302471091.699268367
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11900 is not tested in classification assay
Integrated Annotations for CG11900 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
guanosine tetraphosphate catabolic processGO:0015971inferred from direct assay
response to starvation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activityGO:0008893inferred from direct assay
metal ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11900 in FlyBase
FLIGHTClick here to see CG11900 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11900 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11900
Entrez GeneEntrez Gene page for CG11900
UniprotUniprot page for CG11900

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)