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Gene Page - CG Number : CG11901
Gene Summary - CG11901:

CG11901: The gene Ef1γ is referred to in FlyBase by the symbol Dmel\Ef1γ (CG11901, FBgn0029176). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation elongation factor activity. There is experimental evidence that it is involved in the biological process: autophagic cell death; salivary gland cell autophagic cell death. 14 alleles are reported. The phenotypes of these alleles are annotated with: eye; ommatidium. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Glutathione S-transferase/chloride channel, C-terminal; Thioredoxin-like fold; Translation elongation factor EF1B, gamma chain, conserved. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed within 00-12 hour embryonic stages, during early larval stages.

Gene summary for CG11901 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11901:CG11901 is perturbed in following parameters in primary screen: NuSize
CG11901 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11901.
Cell Count:
CG_NumberCategoryR1R2R3
CG11901Primary screen144406145
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11901:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
211296-0.344141332-0.8349213860.745158284-1.154713064-0.827019405-1.236685496-1.797663395-1.739148691-3.284314798-0.497677836-0.691014687-0.1155699210.118723485-0.424507115-0.147179917-1.18843503-1.1668825-1.8775294020.340775683-3.0872268490.5208375853.2812684461.793350491
212200.427942101-0.552964147-0.218349914-0.9825068290.2101490580.4438915910.071052150.746971411.142522955-0.0585933060.11741119-0.559297584-0.11252130.208496823-0.816489333-0.0772258770.4136042710.1230541370.2682849271.0790436760.153026575-0.853400331-0.594946994
213170-0.419968208-0.819615661-0.4744089440.438995191-1.349775792-1.2868321-1.584437936-1.397603022-3.494509085-0.461470259-0.699088811-0.918903925-0.185479602-1.3884277541.071681165-0.436431218-0.046756745-1.479951436-0.947042411-3.4496846031.3994209143.6312226450.873428808
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11901 is not tested in classification assay
Integrated Annotations for CG11901 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
translational elongationGO:0006414inferred from sequence or structural similarity
autophagic cell death
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
lipid particleGO:0005811inferred from direct assay
cytosol
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
translation elongation factor activityGO:0003746inferred from sequence or structural similarity
translation elongation factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11901 in FlyBase
FLIGHTClick here to see CG11901 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11901 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11901
Entrez GeneEntrez Gene page for CG11901
UniprotUniprot page for CG11901

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)