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Gene Page - CG Number : CG11907
Gene Summary - CG11907:

CG11907: The gene Equilibrative nucleoside transporter 1 is referred to in FlyBase by the symbol Dmel\Ent1 (CG11907, FBgn0031250). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: nucleoside transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process: nucleoside transport. 4 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; scutellar bristle; wing. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Equilibrative nucleoside transporter; Major facilitator superfamily domain, general substrate transporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late larval stages, during early pupal stages.

Gene summary for CG11907 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11907:CG11907 is perturbed in following parameters in primary screen: Fmph2
CG11907 is perturbed in following parameters in classification assay (fluid): NuCirc-(fld) NuFluct+(fld)
CG11907 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11907.
Cell Count:
CG_NumberCategoryR1R2R3
CG11907Primary screen578287264
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11907:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2112980.4605562930.6971356440.087998448-0.7422678060.4315599722.0119733134.3465501741.9404581792.1019390663.0087637461.1150384870.6670205150.9714498941.575299996-0.2369544420.1813019373.1604888070.9902292431.2766366092.440948451-0.7088574834.1817441113.764621935
212182.078795321-0.0143385520.6097321840.310848375-0.2388167230.560970753.132165890.0083810.797955035-0.1504549451.2306862620.980811320.612837359-0.204222272-0.687717336-0.8684148270.5299885150.858966562-0.4447986351.1320327980.1467202261.3320450940.317941016
213168-0.1869414421.1094293631.5069491480.512865222-0.049639103-0.202908542-0.710912091-0.5936263710.6097492290.681657207-0.302885548-0.1960164950.4840262910.559041669-1.061325394-0.39804592-0.257557430.9566350890.8581002780.515477257-0.956571427-0.018151319-0.15371572
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11907Slide21C0.8681.0810.9171.033
CG11907Slide21O0.8941.2460.9710.707
CG11907Slide21P0.8150.9700.9461.055
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11907 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
nucleoside transportGO:0015858inferred from sequence or structural similarity with HGNC_gene:SLC29A1; HGNC:11003 inferred from sequence or structural similarity with HGNC_gene:SLC29A2; HGNC:11004
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from sequence model
integral to membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
nucleoside transmembrane transporter activityGO:0005337inferred from sequence or structural similarity with HGNC_gene:SLC29A2; HGNC:11004 inferred from sequence or structural similarity with HGNC_gene:SLC29A1; HGNC:11003
Other annotations
DatabaseLink
FlyBaseClick here to see CG11907 in FlyBase
FLIGHTClick here to see CG11907 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11907 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11907
Entrez GeneEntrez Gene page for CG11907
UniprotUniprot page for CG11907

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)