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Gene Page - CG Number : CG11912
Gene Summary - CG11912:

CG11912: This gene is referred to in FlyBase by the symbol Dmel\CG11912 (FBgn0031248). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: serine-type endopeptidase activity. It is reported to be involved in the biological process: proteolysis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1/S6, chymotrypsin/Hap, active site; Peptidase S1A, chymotrypsin-type; Peptidase cysteine/serine, trypsin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected. Peak expression observed during late larval stages.

Gene summary for CG11912 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11912:CG11912 is perturbed in following parameters in primary screen: Fmph1 Fmph2 NuSize Tclc
CG11912 is perturbed in following parameters in classification assay (fluid): LP_Fint2- SP_Fclc- SP_Fnum+
CG11912 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11912.
Cell Count:
CG_NumberCategoryR1R2R3
CG11912Primary screen50447749
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11912:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22130.8713599361.0676854013.164763429-0.4809005280.8347834587.8813707811.530746779.8824711973.6349401550.6474468683.051654337-0.1921275050.4839622610.528455147-0.3393689490.7666728281.4494018042.3312310431.1288362566.268970358-0.0452909973.1951863042.762926722
2221630.819341431-0.5077312582.1696473581.635865473-0.2911949653.1032858454.3317931722.382337332.550259804-0.504050740.8830468220.632044750.066351220.326799330.2870995760.2551281830.5055104481.4985987420.5113801143.146021666-0.4459184013.7931699031.088353019
223133-0.20438659-0.4770772470.4603321361.067395689-3.176734836-2.93607056-2.348347571-2.841863132-6.060033264-0.733655881-1.6694925010.142118179-0.7625256670.4143645341.866829467-1.261591561-0.254300256-1.578939584-1.00224747-4.9316385674.176807517-0.020109381-0.414059139
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11912Slide21C0.2190.8621.0100.784
CG11912Slide21O0.9711.1641.4120.465
CG11912Slide21P0.4710.9051.0590.639
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11912 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
proteolysisGO:0006508non-traceable author statement
proteolysis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
serine-type endopeptidase activityGO:0004252non-traceable author statement
serine-type endopeptidase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11912 in FlyBase
FLIGHTClick here to see CG11912 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11912 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11912
Entrez GeneEntrez Gene page for CG11912
UniprotUniprot page for CG11912

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)