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Gene Page - CG Number : CG11913
Gene Summary - CG11913:

CG11913: This gene is referred to in FlyBase by the symbol Dmel\CG11913 (FBgn0039331). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process: mitochondrial electron transport, NADH to ubiquinone. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: NAD(P)H-quinone oxidoreductase subunit D/H; NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed at stages throughout the pupal period, in adult male stages.

Gene summary for CG11913 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11913:CG11913 is perturbed in following parameters in primary screen: Rto2
CG11913 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11913.
Cell Count:
CG_NumberCategoryR1R2R3
CG11913Primary screen30177289
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11913:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22140.087183354-0.522393650.3276890711.7402400520.5324935840.5646858562.5504554891.1018959770.433234292-0.9343051180.5291317270.095086311-0.6584140380.002405043-0.3938353910.221652864-0.3313588670.220347179-0.8586000971.5127178940.0085143430.37309233-0.161624473
2221624.8133907213.4340525392.4700442230.204312725-1.7351963912.629354804-2.5144650321.983517329.97016841517.15686581.7696956196.94828931111.0499884810.032379447.2423493435.19536501717.426230759.88887755320.834506167.4991020360.127677554-0.0731641160.312080207
2231321.2239286740.145212379-0.4817658732.152132817-0.1949272470.138524433-0.02025206-0.152986337-0.222202185-0.5380593030.315080764-0.0700968933.1843118580.0195422410.087395310.009353575-0.436657386-0.146703163-0.1600875070.419247965-0.7938715861.383308766-0.634316869
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11913 is not tested in classification assay
Integrated Annotations for CG11913 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
mitochondrial electron transport, NADH to ubiquinoneGO:0006120inferred from sequence or structural similarity with UniProtKB:O95299
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
mitochondrial respiratory chain complex IGO:0005747inferred from sequence or structural similarity with UniProtKB:P17694
mitochondrial respiratory chain complex I
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
NADH dehydrogenase (ubiquinone) activityGO:0008137inferred from sequence or structural similarity with UniProtKB:P17694
NADH dehydrogenase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11913 in FlyBase
FLIGHTClick here to see CG11913 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11913 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11913
Entrez GeneEntrez Gene page for CG11913
UniprotUniprot page for CG11913

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)