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Gene Page - CG Number : CG11921
Gene Summary - CG11921:

CG11921: The gene forkhead domain 96Ca is referred to in FlyBase by the symbol Dmel\fd96Ca (CG11921, FBgn0004897). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity. It is reported to be involved in the biological process: embryo development. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Transcription factor, fork head; Transcription factor, fork head, conserved site; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.

Gene summary for CG11921 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11921:CG11921 is perturbed in following parameters in primary screen: Fmph2
CG11921 is perturbed in following parameters in classification assay (fluid): LP_Fint1+ LP_Fint2+ LP_Fint4- Rto2- Rto3-
CG11921 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11921.
Cell Count:
CG_NumberCategoryR1R2R3
CG11921Primary screen413434199
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11921:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22191.2361805951.2999500660.9286050340.1279993020.1403949911.781530453.409757931.1694592961.2184266770.9193534240.23190149-0.523374860.264897030.4893541590.6718443690.2568860311.5313739010.3196346050.5573292331.153834029-0.5158604151.1962855312.082178369
222157-0.558431221-0.7167062331.143296051-0.5547138260.001497131.6449268953.3054193441.7947892622.8863759971.220233093.901469999-0.1425926071.7996312131.409656469-0.5319344250.6817675053.2330033085.200077854.4180342433.634994086-0.3272157071.19542298-0.164402705
2231273.4994863541.1182090910.758011205-0.236954786-0.3731790710.3834435631.0862122950.146693979-0.478977249-1.134965898-0.4581258641.012347703-0.2149572973.121874133-0.3429729910.47308265-0.665290919-0.414268523-0.8014439461.7045630642.634719501-0.671415890.310759414
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11921Slide21C0.1011.4321.6481.135
CG11921Slide21O0.3100.8080.4370.859
CG11921Slide21P0.6361.0041.0080.791
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11921 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
embryo developmentGO:0009790non-traceable author statement
regulation of transcription, DNA-dependent
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from sequence or structural similarity with EMBL:AF071554
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700inferred from sequence or structural similarity with EMBL:AF071554
sequence-specific DNA binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11921 in FlyBase
FLIGHTClick here to see CG11921 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11921 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11921
Entrez GeneEntrez Gene page for CG11921
UniprotUniprot page for CG11921

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)