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Gene Page - CG Number : CG11922
Gene Summary - CG11922:

CG11922: The gene forkhead domain 96Cb is referred to in FlyBase by the symbol Dmel\fd96Cb (CG11922, FBgn0004898). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity. It is reported to be involved in the biological process: embryo development. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Transcription factor, fork head; Transcription factor, fork head, conserved site; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 06-12 hour embryonic stages.

Gene summary for CG11922 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11922:CG11922 is perturbed in following parameters in primary screen: Fclc Fmph2 Tclc
CG11922 is not perturbed in classification assay (fluid).
CG11922 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11922.
Cell Count:
CG_NumberCategoryR1R2R3
CG11922Primary screen699502128
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11922:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
221101.2232957850.3675728210.7723187280.3582388131.0846773973.6404905575.9165618182.7823106923.1708240480.5555413890.299228156-0.2622621161.8933039170.7974403550.6014936880.3914146082.718683591.4250722292.2088226763.6683199121.3589346071.2458820931.166611157
2221561.6873412411.245589851.44442550.1066244220.0192835412.9486579365.1709416962.1968875114.213336741.6311166673.1138760890.0696602191.7429694270.624400374-0.1738069660.5675270591.9571079735.8469038512.2558500144.7285749970.333171653.1178880510.851938115
2231260.176004166-0.315332419-0.553757984-0.272636866-1.197148584-0.7986273280.019035487-0.366565419-1.495060964-0.0536660230.178348624-0.9498821321.589544123-0.378462991-0.346098972-1.726901052-0.2692764230.313781109-0.730411377-1.5585593181.83314311-1.270620196-0.338591347
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11922Slide21C0.6010.2361.1271.096
CG11922Slide21O0.6250.0691.0391.262
CG11922Slide21P0.4300.1520.9421.064
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11922 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
embryo developmentGO:0009790non-traceable author statement
regulation of transcription, DNA-dependent
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from sequence or structural similarity with EMBL:U90538
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700inferred from sequence or structural similarity with EMBL:U90538
sequence-specific DNA binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11922 in FlyBase
FLIGHTClick here to see CG11922 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11922 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11922
Entrez GeneEntrez Gene page for CG11922
UniprotUniprot page for CG11922

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)