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Gene Page - CG Number : CG1193
Gene Summary - CG1193:

CG1193: The gene katanin p60-like 1 is referred to in FlyBase by the symbol Dmel\kat-60L1 (CG1193, FBgn0037375). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATPase activity; microtubule binding. There is experimental evidence that it is involved in the biological process: positive regulation of dendrite morphogenesis; neuron remodeling. 9 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; dendrite; class IV dendritic arborizing neuron; dorsal multidendritic neuron ddaC; dorsal cluster neuron. It has 8 annotated transcripts and 8 annotated polypeptides. Protein features are: AAA+ ATPase domain; ATPase, AAA-type, conserved site; ATPase, AAA-type, core; Vps4 oligomerisation, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed in adult male stages.

Gene summary for CG1193 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1193:CG1193 is perturbed in following parameters in primary screen: Rto1
CG1193 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1193.
Cell Count:
CG_NumberCategoryR1R2R3
CG1193Primary screen289510606
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1193:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG1193 is not tested in classification assay
Integrated Annotations for CG1193 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
microtubule severingGO:0051013inferred from sequence or structural similarity with NCBI_gi:3283072
microtubule-based process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
endoplasmic reticulumGO:0005783inferred from sequence or structural similarity with EMBL:AF052191
katanin complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ATPase activityGO:0016887inferred from sequence or structural similarity with EMBL:AF052191
microtubule binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG1193 in FlyBase
FLIGHTClick here to see CG1193 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1193 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1193
Entrez GeneEntrez Gene page for CG1193
UniprotUniprot page for CG1193

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)