Home Browse SearchHelp DownloadGroup

.:: RNAiDB - Gene Page ::.
Gene Page - CG Number : CG11949
Gene Summary - CG11949:

CG11949: The gene coracle is referred to in FlyBase by the symbol Dmel\cora (CG11949, FBgn0010434). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: cytoskeletal protein binding. There is experimental evidence that it is involved in the biological process: adult somatic muscle development; embryonic morphogenesis; maintenance of imaginal disc-derived wing hair orientation; regulation of tube size, open tracheal system; establishment of glial blood-brain barrier. 44 alleles are reported. The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; organ system subdivision; external compound sense organ; adult; non-connected developing system; apical junction complex; adult segment; septate junction; dorsal trunk primordium; cell-cell junction; sense organ; embryonic foregut. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Band 4.1 domain; Band 4.1 family; Band 4.1, C-terminal; FERM adjacent (FA); FERM central domain; FERM conserved site; FERM domain; FERM, C-terminal PH-like domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; Pleckstrin homology-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages.

Gene summary for CG11949 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11949:CG11949 is not perturbed in primary screen.
CG11949 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11949.
Cell Count:
CG_NumberCategoryR1R2R3
CG11949Primary screen477333309
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11949:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
221211.047246445-0.708897448-0.0541245120.7306574320.704885550.8210786011.082646290.7331301520.5824940630.7264366120.3005977140.3953317140.7735594951.471674251-0.132365080.3710774391.8242354620.2554454890.5568030360.8051214760.0842787660.782139656-0.376735603
2221750.780017711-0.711310546-0.733118930.178662335-0.5384201821.4939464762.6760131970.9761580111.2296091490.9806617233.052569725-0.7801445710.7454656490.554643397-0.302449551-0.5129160665.4761022632.7068154590.6774857211.961925478-0.671962801-0.3248310340.618883706
2231458.2838320285.7569630811.307384076.0862179410.7822276891.9888120441.4646090651.93183995517.790297150.222575852-0.26107525326.69876627.8243543423.847395910.1829288860.3534272241.1715409441.2830147511.2420859810.383848971.26597222617.457001874.299662467
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11949 is not tested in classification assay
Integrated Annotations for CG11949 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
embryonic morphogenesisGO:0048598inferred from mutant phenotype
dorsal closure
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
septate junctionGO:0005918inferred from direct assay
fusome
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
cytoskeletal protein bindingGO:0008092inferred from sequence or structural similarity
actin binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11949 in FlyBase
FLIGHTClick here to see CG11949 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11949 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11949
Entrez GeneEntrez Gene page for CG11949
UniprotUniprot page for CG11949

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)