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Gene Page - CG Number : CG11958
Gene Summary - CG11958:

CG11958: The gene Calnexin 99A is referred to in FlyBase by the symbol Dmel\Cnx99A (CG11958, FBgn0015622). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: unfolded protein binding. There is experimental evidence that it is involved in the biological process: rhodopsin biosynthetic process; regulation of calcium ion transport into cytosol; retina homeostasis. 9 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system subdivision; external compound sense organ; organ system; peripheral nervous system; cytoplasmic part; histaminergic neuron; organelle; eo support cell; intracellular organelle; Golgi apparatus; adult segment. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Calreticulin/calnexin; Calreticulin/calnexin, P; Calreticulin/calnexin, conserved site; Concanavalin A-like lectin/glucanase, subgroup; Concanavalin A-like lectin/glucanases superfamily. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.

Gene summary for CG11958 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11958:CG11958 is not perturbed in primary screen.
CG11958 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11958.
Cell Count:
CG_NumberCategoryR1R2R3
CG11958Primary screen097188
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11958:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22127-5.84551832-6.033592434-5.867532346-6.656794608-5.071758876-8.134226273-7.328896024-8.135789953-9.605507214-6.45717428-6.031254045-5.600860299-5.764631487-6.683370293-5.786486382-5.148139996-7.345754694-5.972935544-6.801117736-9.442556205-4.945889033-3.770451742-3.921517382
2221691.15972949-0.625733943-0.098743398-0.467522365-2.212487692-1.048565111-1.243458048-1.529380999-2.924785186-1.421164174-0.6359950290.017854715-0.7556802260.726721861-0.980373384-1.520535579-1.522004149-1.447396079-2.209630775-2.5319897521.321430728-0.066598916-1.002918576
223139-0.824777912-1.345572809-0.6716321250.136331524-0.854380565-0.398390453-0.895009836-0.02002856-0.8873215630.06988523-0.06321729-0.5007743870.3184906840.486615963-0.388348899-1.288819963-0.819195981-0.208153451-0.694503081-0.658806068-0.4174779820.0180665790.29116291
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11958 is not tested in classification assay
Integrated Annotations for CG11958 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
protein foldingGO:0006457non-traceable author statement
rhodopsin biosynthetic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
plasma membraneGO:0005886inferred from sequence or structural similarity
endoplasmic reticulum
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
unfolded protein bindingGO:0051082inferred from sequence or structural similarity with EMBL:L23865
calcium ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11958 in FlyBase
FLIGHTClick here to see CG11958 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11958 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11958
Entrez GeneEntrez Gene page for CG11958
UniprotUniprot page for CG11958

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)