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Gene Page - CG Number : CG11967
Gene Summary - CG11967:

CG11967: The gene Carbonic anhydrase β is referred to in FlyBase by the symbol Dmel\CAHβ (CG11967, FBgn0037646). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: carbonate dehydratase activity. There is experimental evidence that it is involved in the biological process: carbon utilization. 5 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Carbonic anhydrase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.

Gene summary for CG11967 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11967:CG11967 is perturbed in following parameters in primary screen: Fmph2 Tclc Tmph2
CG11967 is perturbed in following parameters in classification assay (fluid): LP_Fint1+ LP_Fmph3+ SP_Fint1+ SP_Fint2+ SP_Fint3+ SP_Fint4+ SP_Fmph2- SP_Fnum-
CG11967 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11967.
Cell Count:
CG_NumberCategoryR1R2R3
CG11967Primary screen477299105
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11967:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
221332.285005072-0.5468583730.1171976930.3779538580.4183759274.2460691665.1656797855.1756982062.6067484222.5982981562.586539736-0.0481889031.2703654931.3395092110.517595837-0.0676763492.3070861043.0322883821.2922157283.006006714-0.8750958650.7113554630.092129345
222193-0.0380973981.4312202913.2122830591.489322891-0.6286108862.4998510344.5350883452.6920652252.8014563381.9882238463.571369002-0.2883892660.9516125881.6305532690.340274219-0.0980176181.6209254145.3864964382.3727180723.235354689-0.6049999730.3822441580.808611081
2231031.019821144-0.768345338-0.108909916-0.547677936-1.556030707-1.283764135-1.164443107-1.348590211-4.0632163031.098005016-0.136676996-0.193575019-2.0702223860.1448809022.239247488-1.2838797010.94763375-1.538536970.881235615-3.166337780.662654773-0.7504496790.702710024
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11967Slide8C0.3790.9921.3821.040
CG11967Slide8O0.1431.0251.1971.113
CG11967Slide8P0.0211.0821.1851.180
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11967 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
carbon utilizationGO:0015976inferred from direct assay
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
mitochondrionGO:0005739inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
carbonate dehydratase activityGO:0004089inferred from direct assay
zinc ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11967 in FlyBase
FLIGHTClick here to see CG11967 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11967 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11967
Entrez GeneEntrez Gene page for CG11967
UniprotUniprot page for CG11967

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)